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Extracellular vesicles for diagnosis and treatment of breast cancer
SHORT DESCRIPTION
Novel methods for detecting cancer through exosome analysis and bioengineered exosomes specifically designed to target cancer stem cells (CSCs).
INVENTORS
Huiping Liu*, MD, PhD
Associate Professor, Pharmacology, Medicine (Hematology and Oncology), Northwestern University Feinberg School...
Published: 2/6/2026
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Inventor(s):
Keywords(s): Biomarker, Breast cancer, Cancer/Oncology, Diagnostics, Imaging, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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The use of complex or fusion protein of soluble MIC (Smic) and antibody to treat MIC-negative cancer
NU 2019-146
INVENTORS
Jennifer Wu*
SHORT DESCRIPTION
A fusion protein complex comprising soluble MIC and a non-blocking sMIC-neutralizing antibody that effectively activates CD8 T cells for the treatment of MIC-negative cancer.
BACKGROUND
Effective T cell co-stimulation is critical for durable tumor control, yet many current immunotherapies...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Antibody, Cancer/Oncology, Research tool
Category(s): Life Sciences > Therapeutics
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2-(Pyridin-3-yl)quinazoline compounds as glucocerebrosidase modulators
✅ Feedback form for Tech ID 2015-064
PROPOSED TITLE: 2-(Pyridin-3-yl) quinazoline Compounds as Glucocerebrosidase Modulators
NU 2015-064
INVENTORS
Richard Silverman*
Dimitri Krainc
Jianbin Zheng
SHORT DESCRIPTION
Novel substituted quinazoline compounds that modulate glucocerebrosidase activity, offering a promising therapeutic approach for...
Published: 11/18/2025
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Inventor(s):
Keywords(s): Neurodegenerative disease, Neurologic disease, PD - Parkinson's Disease, Research tool, Therapeutics
Category(s): Life Sciences > Therapeutics
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Projected Beam Pen Lithography for Benchtop High Resolution Maskless Photolithography of Large Areas
NU 2012-090
INVENTORS
Chad Mirkin (Northwestern University, Department of Chemistry)*
Keith Brown
Shu He
Guoliang Liu
Xing Liao
Wooyoung Shim
Abrin Schmucker
SHORT DESCRIPTION
This lithography system uses a projected beam pen method to directly pattern surfaces. It produces sub-100nm features quickly without the need for expensive masks.
BACKGROUND
Current...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Lithography, Nanomaterials, Nanotechnology, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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A Biological Marker for Concussion
NU 2016-016
INVENTORS
Nina Kraus*
Trent Nicol
Travis White-Schwoch
SHORT DESCRIPTION
This technology provides a method for objectively identifying non-penetrating brain injuries by analyzing the brain’s frequency following response (FFR) to an acoustic stimulus. It offers a non-invasive alternative that improves diagnostic precision and...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Biomarker, Brain injury, Devices, Diagnostics, Electrophysiology, Health IT, Medical device, Neurologic disease, Research tool
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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A platform for mapping reactive cysteines within the immunopeptidome
NU 2024-044
INVENTORS
Xiaoyu Zhang*
Chenlu Zhang
Chen Zhou
SHORT DESCRIPTION
This invention provides novel chemical probes for mapping reactive cysteine residues within the major histocompatibility complex class I (MHC-I) immunopeptidome.
BACKGROUND
The immune system's recognition of infected or malignant cells hinges on the presentation...
Published: 12/11/2025
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Inventor(s):
Keywords(s): Biomarker, Immunology, Research reagent, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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TauSeeK: Disease Specific Tau Protein Fibrils & Seeding Proteins
NU 2024-154
INVENTORS
Songi Han*
Austin Dubose
Michael Vigers
Andrew Longhini
Vishnu Vijayan
Kenneth Kosik
Samuel Lobo
Peter C. Ryffel
Lokeswara Rao Potnuru
Karen Tsay
Chung-Ta Han
SHORT DESCRIPTION
Compositions, kits, and methods for generating synthetic miniature tau peptides and fibrils, and synthetic full-length pathogenic tau...
Published: 1/14/2026
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Inventor(s):
Keywords(s): AD - Alzheimer’s Disease, HD - Huntington's Disease, Neurodegenerative disease, Neurology, PD - Parkinson's Disease, Research tool
Category(s): Life Sciences > Therapeutics
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Nanocytological and Molecular Analysis of Fecal Colonocytes for Colon Cancer Screening
NU 2010-131
INVENTORS
Vadim Backman*
Dhwanil Damania
Dhananjay Kunte
Hariharan Subramanian
Hemant Roy
Mart De La Cruz
SHORT DESCRIPTION
This technology offers a novel fecal test that detects nanoarchitectural and molecular markers in colonocytes. It delivers a minimally invasive screening method for early detection of colon cancer.
BACKGROUND
Colorectal...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Cancer/Oncology, Colon cancer, Diagnostics, Drug screening, Imaging, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Artificial Extracellular Matrix for Enhanced Maturation of Human iPSCs-derived Neurons
Artificial Extracellular Matrix for Enhanced Maturation of Human iPSCs-derived Neurons
NU 2018-157
Peptide amphiphile nanofibers enhance neuron maturation by promoting high mobility while reducing cell aggregation.
INVENTORS
Samuel I. Stupp
Zaida Alvarez Pinto
Juan Alberto Ortega Cano
Kohei Sato
Evangelos Kiskinis
SHORT DESCRIPTION
A...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Neurology, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Rapid Nanomechanical Diagnostic Assay for SARS-CoV-2 and Other Pulmonary Diseases Detection
NU 2021-142
INVENTORS
Gajendra Shekhawat*
Vinayak Dravid
SHORT DESCRIPTION
This invention introduces a nanomechanical diagnostic assay leveraging microcantilevers for the rapid and specific detection of SARS-CoV-2 antigens, achieving results in under 10 minutes with high sensitivity and selectivity.
BACKGROUND
Rapid detection of respiratory...
Published: 11/6/2025
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Inventor(s):
Keywords(s): COVID-19, Diagnostics, Pulmonary disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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