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Netrin-1 mimetic peptide amphiphiles
Netrin-1 Mimetic Peptide Amphiphile Assemblies
NU 2024-174
INVENTORS
Samuel Stupp*
Cara Smith
Zaida Alvarez Pinto
SHORT DESCRIPTION
Nanofiber-shaped supramolecular assemblies that mimic netrin-1 bioactivity to stimulate neurite growth and synaptic maturation for enhanced CNS regeneration.
BACKGROUND
Neurotrophic factors are essential for...
Published: 2/20/2026
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Inventor(s):
Keywords(s): AD - Alzheimer’s Disease, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Nanotechnology, Neurodegenerative disease, Regenerative medicine, SCI - Spinal cord injury, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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Sliding Bioactive Peptides for Therapeutic Delivery
NU 2023-142
INVENTORS
Samuel I. Stupp*
Federico Lancia
Madison E. Strong
Matias A. Alvarez-Saavedra
SHORT DESCRIPTION
This technology involves the design and engineering of peptide amphiphile nanofibers that deliver bioactive peptides both extra- and intra-cellularly. The bioactive peptides can slide along these structures...
Published: 1/9/2026
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Inventor(s):
Keywords(s): Biomaterials, CNS - Central Nervous System, Drug delivery, Neurologic disease, Neurology, Regenerative medicine, SCI - Spinal cord injury, Therapeutics
Category(s): Life Sciences > Therapeutics
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Human Spinal Cord Injury Organoids for Therapeutic Discovery
NU 2023-116
INVENTORS
Nozomu Takata
Nicholas Sather
Samuel Stupp*
SHORT DESCRIPTION
A human organoid model to simulate spinal cord injury in vitro and test potential therapeutics.
BACKGROUND
Injury in organs triggers cellular and molecular rearrangements that induce intrinsic repair and regeneration, but the human central nervous system has...
Published: 1/16/2026
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Inventor(s):
Keywords(s): In vitro models, Neurology, Research tool, SCI - Spinal cord injury
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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