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Netrin-1 mimetic peptide amphiphiles
Netrin-1 Mimetic Peptide Amphiphile Assemblies
NU 2024-174
INVENTORS
Samuel Stupp*
Cara Smith
Zaida Alvarez Pinto
SHORT DESCRIPTION
Nanofiber-shaped supramolecular assemblies that mimic netrin-1 bioactivity to stimulate neurite growth and synaptic maturation for enhanced CNS regeneration.
BACKGROUND
Neurotrophic factors are essential for...
Published: 2/20/2026
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Updated: 2/20/2026
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Inventor(s):
Keywords(s): AD - Alzheimer’s Disease, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Nanotechnology, Neurodegenerative disease, Regenerative medicine, SCI - Spinal cord injury, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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Projected Beam Pen Lithography for Benchtop High Resolution Maskless Photolithography of Large Areas
NU 2012-090
INVENTORS
Chad Mirkin (Northwestern University, Department of Chemistry)*
Keith Brown
Shu He
Guoliang Liu
Xing Liao
Wooyoung Shim
Abrin Schmucker
SHORT DESCRIPTION
This lithography system uses a projected beam pen method to directly pattern surfaces. It produces sub-100nm features quickly without the need for expensive masks.
BACKGROUND
Current...
Published: 12/9/2025
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Updated: 11/11/2025
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Inventor(s):
Keywords(s): Lithography, Nanomaterials, Nanotechnology, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 12/9/2025
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Updated: 10/30/2025
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Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Video-Rate Infrared Focal Plane Array Based on Solution-Processed Black Phosphorus Films
NU 2025-012
INVENTORS
Hooman Mohseni*
Mark Hersam*
Simone Bianconi
Vinod Sangwan
SHORT DESCRIPTION
This innovation demonstrates a video-rate infrared focal plane array fabricated by integrating solution-processed black phosphorus films with modified CMOS read-out integrated circuits, enabling high-performance mid-infrared imaging.
BACKGROUND
Conventional...
Published: 3/17/2026
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Updated: 10/17/2025
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Inventor(s):
Keywords(s): Nanomaterials, Nanotechnology
Category(s): Physical Sciences > Engineering & Technology, Physical Sciences > Materials and Industrial Processes
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Electrical Energy Generation Using Metal Nanofilms
NU 2014-102, 2018-154, 2019-155Primary InventorsFranz Geiger*Tom Miller* (CalTech)Short DescriptionMetal nanofilms that convert gravitational energy to electrical energy when aqueous drops roll down their surface.BackgroundHarvesting electrical energy from natural resources is critical to limit the consumption of batteries and fossil fuels. Approaches...
Published: 11/6/2025
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Updated: 5/16/2025
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Inventor(s):
Keywords(s): Cleantech, Energy and Infrastructure, Engineering, Nanotechnology, Novel Energy, Sensors, Thin film
Category(s): Physical Sciences > Energy & Sustainability
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Self-Assembled Borophene/Graphene Nanoribbon Mixed-Dimensional Heterostructures
NU 2021-078
INVENTORS
Mark Hersam*
Eden B Aklile
Qiucheng Li
Xiaolong Liu
SHORT DESCRIPTION
This invention presents a novel method for the synthesis of mixed-dimensional lateral heterostructures with integrated 2D metallic borophene and 1D semiconducting graphene nanoribbons, offering atomically precise metal-semiconductor...
Published: 11/6/2025
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Updated: 4/29/2025
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Inventor(s):
Keywords(s): Electronics & Circuits, Materials, Nanotechnology, Semiconductors & Integrated Circuits
Category(s): Physical Sciences > Materials and Industrial Processes
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Visible Light Photoreduction of CO2 in Pure Water using Quantum Dots as Photosensitizer
Visible Light Photoreduction of CO2 in Pure Water using Quantum Dots as Photosensitizer
NU 2020-225
INVENTORS
Emily Weiss*
Benjamin Nagasing
Francesca Arcudi
Luka Dordevic
Samuel Stupp
SHORT DESCRIPTION
This invention discloses a method for light-driven photocatalytic reduction of CO2 to CO in pure water using colloidal quantum dots as photosensitizers,...
Published: 11/6/2025
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Updated: 4/28/2025
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Inventor(s):
Keywords(s): Carbon Dioxide Management, Carbon Utilization, Catalyst, CCUS, Cleantech, Environment, Nanotechnology, Renewable, Solar
Category(s): Physical Sciences > Materials and Industrial Processes
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Leveraging Lipid-Protein Interactions to Engineer Spatial Organization in Cell-free Systems
NU 2021-231
INVENTORS
Neha Kamat*
Justin Alexander Peruzzi
Jan Steinkuehler
SHORT DESCRIPTION
This innovative method enables the control of membrane protein location and distribution in synthetic lipid membranes using lipid-protein interactions, without chemical conjugation, facilitating the development of advanced cell-free systems.
BACKGROUND
Spatially...
Published: 4/9/2026
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Updated: 2/28/2025
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Inventor(s):
Keywords(s): Drug delivery, Nanomaterials, Nanoparticle, Nanotechnology, Research tool, Synthetic biology, Targeted therapy, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Physical Sciences > Engineering & Technology
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CRISPR Spherical Nucleic Acids
NU 2021-043
INVENTORS
Chad A. Mirkin*
Chi Huang
BACKGROUND
The use of CRISPR/Cas9 systems in genome editing has been limited by the inability to efficiently deliver the key editing components to tissues...
Published: 11/6/2025
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Updated: 5/9/2024
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Inventor(s):
Keywords(s): Genomics, Nanotechnology, Research tool
Category(s): Life Sciences > Therapeutics
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Smart Memtransistors: Learning to Forget On Demand
NU 2021-179
PRIMARY INVENTOR
Jiangtan Yuan
Stephanie Elizabeth Liu
Vinod Kumar Sangwan
Amit R. Trivedi
Mark C. Hersam*
SHORT DESCRIPTION
A reconfigurable memtransistor that can dynamically adapt to new learning tasks
BACKGROUND
Recent AI advances have been possible due to GPU enabled parallel computing. However, this high computing capacity is not...
Published: 11/6/2025
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Updated: 12/17/2021
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Inventor(s):
Keywords(s): Artificial Intelligence & Machine Learning, Computer hardware, Data processing/analysis, Data storage, Electronics & Circuits, Nanotechnology, Platform technology, Quantum computing, Semiconductors & Integrated Circuits
Category(s): Physical Sciences > Materials and Industrial Processes, Physical Sciences > Engineering & Technology
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