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Anti-CD73 Monoclonal Antibody for Enhanced Cancer Immunotherapy
NU 2020-207
INVENTORS
Bin Zhang*
Siqi Chen
Jie Fan
SHORT DESCRIPTION
This invention comprises novel anti-CD73 monoclonal antibody compositions that recognize and inhibit mouse and human CD73.
BACKGROUND
CD73, an ecto-enzyme associated with adenosine metabolism, is an emerging immune checkpoint that promotes tumor progression by suppressing...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Immunology, Immunotherapy
Category(s): Life Sciences > Therapeutics
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New Lipiodol Formulation for Treating Hepatocellular Carcinoma with Transarterial Chemoimmunoembolization
NU 2021-148
INVENTORS
Dong Hyun Kim*
Heegon Kim
SHORT DESCRIPTION
A new Lipiodol formulation designed to improve the efficacy and safety of transarterial chemoembolization in combination with immunotherapy.
BACKGROUND
Transarterial chemoembolization...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cancer/Oncology, Drug delivery, Gastrointestinal and Hepatic disease, Immunology, Immunotherapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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Methods and Compounds that block the release of enveloped viruses from cells
NU 2019-084
INVENTORS
Jonathan Leis*
Chi-Hao Luan
SHORT DESCRIPTION
Antiviral agents targeting a broad range of enveloped viruses for pan-viral therapeutics
BACKGROUND
To date, there are very few shared mechanisms identified between families of shared viruses. As such, there is minimal development of a broad-spectrum antiviral. Enveloped viruses...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Immunology, Immunotherapy, Infectious disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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Immuno-Ablation Agent for Combination Therapy Against Solid Tumors
NU 2022-058
INVENTORS
Dong Hyun Kim*
Kijung Kwak
Bo Yu
SHORT DESCRIPTION
A method of co-delivering immune modulating agents during ethanol ablation of solid tumors
BACKGROUND
Ethanol ablation therapy is a simple and inexpensive method commonly employed to shrink solid tumors. Like other tumor ablation techniques, such as radiofrequency ablation,...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cancer/Oncology, Drug delivery, Immunology, Immunotherapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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IDO-PROTACs for Improving the Anti-Cancer Immune Response
NU 2020-137
INVENTORS
Derek Wainwright*
Gary Schiltz
SHORT DESCRIPTION
IDO-PROTAC that target immunosuppressive IDO activity via degradation
ABSTRACT
The median survival of primary GBM patients following aggressive surgical intervention, radiotherapy,chemotherapy, and tumor treating fields (TTF) is only ~14-16 months. Indoleamine 2,3-dioxygenase...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cancer/Oncology, Immunotherapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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