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Biomimetic HDL Nanoparticles for Treatment of Cancer, Immune and Inflammatory Disorders, and Cardiovascular Disease
SHORT DESCRIPTION
Self-assembling biomimetic high-density lipoprotein nanoparticle (HDL NP) platform technology with a soft organic core, designed to more closely replicate key functional properties of mature human HDL for therapeutic use in cardiovascular disease, cancer, and inflammatory/immune disorders.
INVENTORS
Colby Thaxton*
Northwestern...
Published: 7/1/2026
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Updated: 6/16/2026
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Inventor(s):
Keywords(s): Atherosclerosis, Autoimmune disease, BIO2026, Breast cancer, Cancer/Oncology, Cardiology and Cardiovascular disease, Gene therapy, Immunology, Immunotherapy, Inflammation, Nanomaterials, Nanoparticle, Nanotechnology, Nucleic Acids, Platform technology, Prostate cancer, Research tool, Small molecule, Targeted therapy, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Therapeutics
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Assembly of Vaccines Using Cell-Free Integration of Viral Membrane Proteins into Liposomes
SHORT DESCRIPTION
A cell-free method that assembles vaccines by integrating viral membrane proteins into liposomes, enabling rapid prototype production without cold chain requirements.
INVENTORS
Neha Kamat*
McCormick School of Engineering, Department of Biomedical Engineering
Hector Aguilar-Carreno
Susan...
Published: 6/16/2026
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Updated: 6/10/2026
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Inventor(s):
Keywords(s): BIO2026, Immunology, Infectious disease, Nanomaterials, Nanoparticle, Nanotechnology, Synthetic biology, Vaccine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Northwestern Startup: NanoIntegris, Inc. (Acquired by Raymor Industries)
Founded: 2006
Northwestern Inventor:
Mark Hersam
McCormick School of Engineering and Applied Science
Department of Material Science and Engineering
NanoIntegris is a leading supplier of premium single- and double-walled carbon nanotubes (SWNT, DWNT). The technology separates nano-tubes by diameter and/or electronic type (i.e., metal vs. semiconductor)....
Published: 6/22/2026
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Updated: 5/5/2026
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Inventor(s):
Keywords(s): Carbon nanotube, Graphene, Nanomaterials, Nanotechnology, Semiconductors & Integrated Circuits, Startup with Northwestern IP
Category(s): Physical Sciences > Materials and Industrial Processes
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GDNF-Mimetic Self-Assembling Supramolecular Nanostructure to Enhance Survival and Function of Dopaminergic Neurons for Treatment of Parkinson's Disease
NU 2024-175
SHORT DESCRIPTION
A self-assembling bioactive matrix that presents GDNF-mimetic peptides to support the viability, maturation, and function of dopaminergic neurons in cell replacement therapy for treatment of Parkinson’s Disease.
INVENTORS
Samuel Stupp*
Weinberg College of Arts and Sciences, Department...
Published: 6/16/2026
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Updated: 4/30/2026
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Inventor(s):
Keywords(s): BIO2026, Biologic, Biomaterials, Cell delivery, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Scaffold, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology
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Targeted Nanofiber Therapy for Atherosclerosis – Enhanced Plaque Regression via Precise Drug Delivery
SHORT DESCRIPTION
Nanofiber-based drug delivery system that targets atherosclerotic plaque and delivers a therapeutic agent locally to induce plaque regression for management of cardiovascular disease.
INVENTORS
Samuel Stupp*
Weinberg College of Arts and Sciences, Department of Chemistry
* Principal Investigator
NU...
Published: 6/16/2026
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Updated: 4/30/2026
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Inventor(s):
Keywords(s): Atherosclerosis, BIO2026, Biomaterials, Cardiology and Cardiovascular disease, Drug delivery, Nanomaterials, Nanotechnology, Self-assembly, Smart/Functional materials, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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Netrin-1 Mimetic Peptide Amphiphile Assemblies for Enhanced CNS Regeneration
NU 2024-174
INVENTORS
Samuel Stupp*
Cara Smith
Zaida Alvarez Pinto
SHORT DESCRIPTION
Nanofiber-shaped supramolecular assemblies that mimic netrin-1 bioactivity to stimulate neurite growth and synaptic maturation for enhanced CNS regeneration.
BACKGROUND
Neurotrophic factors are essential for the development and regeneration of neurons; however,...
Published: 6/16/2026
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Updated: 2/20/2026
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Inventor(s):
Keywords(s): AD - Alzheimer’s Disease, BIO2026, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Nanotechnology, Neurodegenerative disease, Regenerative medicine, SCI - Spinal cord injury, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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Projected Beam Pen Lithography for Benchtop High Resolution Maskless Photolithography of Large Areas
NU 2012-090
INVENTORS
Chad Mirkin (Northwestern University, Department of Chemistry)*
Keith Brown
Shu He
Guoliang Liu
Xing Liao
Wooyoung Shim
Abrin Schmucker
SHORT DESCRIPTION
This lithography system uses a projected beam pen method to directly pattern surfaces. It produces sub-100nm features quickly without the need for expensive masks.
BACKGROUND
Current...
Published: 12/9/2025
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Updated: 11/11/2025
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Inventor(s):
Keywords(s): Lithography, Nanomaterials, Nanotechnology, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Methods for assembling peptides into peptide amphiphile nanofibers
TITLE: Peptide Nanofiber Assembly for Enhanced Therapeutic Delivery
NU 2020-081
SHORT DESCRIPTION
This technology uses self-assembling peptide amphiphile nanofibers to protect and deliver therapeutic peptides. It reduces degradation and improves delivery efficiency for advanced treatment applications.
BACKGROUND
Peptide therapeutics offer promise...
Published: 6/16/2026
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Updated: 10/21/2025
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Inventor(s):
Keywords(s): BIO2026, Drug delivery, Infectious disease, Nanomaterials, Neurodegenerative disease, Neurologic disease, Neurology, Neurovascular, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics
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Video-Rate Infrared Focal Plane Array Based on Solution-Processed Black Phosphorus Films
NU 2025-012
INVENTORS
Hooman Mohseni*
Mark Hersam*
Simone Bianconi
Vinod Sangwan
SHORT DESCRIPTION
This innovation demonstrates a video-rate infrared focal plane array fabricated by integrating solution-processed black phosphorus films with modified CMOS read-out integrated circuits, enabling high-performance mid-infrared imaging.
BACKGROUND
Conventional...
Published: 3/17/2026
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Updated: 10/17/2025
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Inventor(s):
Keywords(s): Nanomaterials, Nanotechnology
Category(s): Physical Sciences > Engineering & Technology, Physical Sciences > Materials and Industrial Processes
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Novel Catalysts based on Polyelemental Heterostructured Nanoparticles for Advanced Catalysis and Optical Applications
NU 2018-126
INVENTORS
Chad Mirkin*
Pengcheng Chen
SHORT DESCRIPTION
This technology streamlines nanoparticle design with a one‐pot synthesis that offers precise interface control. It targets catalysis and optical applications for chemical manufacturers and researchers.
BACKGROUND
Controlling phase boundaries in multi-phase nanomaterials remains...
Published: 3/26/2026
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Updated: 10/17/2025
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Inventor(s):
Keywords(s): Materials, Nanomaterials
Category(s): Physical Sciences > Materials and Industrial Processes, Physical Sciences > Engineering & Technology
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