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A Novel Strategy to Block Mitotic Progression for Target Therapy
NU 2019-008
INVENTORS
Yong Wan*
Zhuan Zhou
Junlong Chi
Gary Schiltz
SHORT DESCRIPTION
A novel proteolysis targeting chimera with high in vivo potency against breast cancer
BACKGROUND
Ubiquitination of a protein results in destruction of the protein and, subsequently, the cell itself. A technology known as the proteolysis targeting chimera (PROTAC)...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Breast cancer, Cancer/Oncology, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics
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