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Soft Bio-Integrated Catheter System
NU 2020-150
INVENTORS
John Rogers (Northwestern University, Department of Materials Science and Engineering)*
Igor Efimov (Northwestern University, Department of Biomedical Engineering, Medicine)*
Roozbeh Ghaffari (Northwestern University, Department of Biomedical Engineering)*
Mengdi Han
SHORT DESCRIPTION
This novel catheter platform delivers...
Published: 11/7/2025
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Inventor(s):
Keywords(s): Gene therapy, Sensors
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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A novel preparation for ultra-small polymer-grafted nanobins for the targeted delivery of biomedicines
NU 2013-210
INVENTORS
SonBinh Nguyen*
Anthony Chipre
SHORT DESCRIPTION
A method of preparation to increase long-term stability and controlled release for ultra-small polymer-grafted nanobins
BACKGROUND
Small unilamellar vesicles (SUVs) are liposomes in 15 – 50 nm range. These components are of growing interest due to their small size, biocompatibility,...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomedical, Devices, Drug delivery, Gene therapy, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Humanized antibody targeting the tumor associated antigen, IL13Ra2
Humanized antibody targeting the tumor associated antigen, IL13Ra2
NU 2020-031
INVENTORS
Irina Balyasnikova*
SHORT DESCRIPTION
A novel antibody that specifically targets glioblastoma cells
BACKGROUND
Glioblastoma is a deadly, incurable disease with a low 5 year survival rate. The current standard of care typically involves surgical resection...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Antibody, Cancer/Oncology, CAR T, Cell therapy, Gene therapy, Neurologic disease, Personalized medicine, Research tool, Therapeutics
Category(s): Life Sciences > Therapeutics
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Gene Therapy for Parkinson's Disease
NU 2021-039
INVENTORS
D. James Surmeier*
Michael Kaplitt
Patricia Gonzalez Rodriguez
SHORT DESCRIPTION
A simple neurological procedure to treat late-stage Parkinson’s Disease patients
BACKGROUND
Approximately 60,000 Americans are diagnosed with Parkinson’s Disease (PD) each year. Although levodopa has been the gold-standard for symptomatic...
Published: 11/6/2025
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Inventor(s):
Keywords(s): CNS - Central Nervous System, Gene therapy, Neurodegenerative disease, Neurology, PD - Parkinson's Disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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Enhancing Gene Silencing by RNAi
NU 2005-063, NU 2005-064, and NU 2006-182 InventorsRichard Carthew* Dinari Harris Young Sik Lee Short DescriptionNovel strategy to improve gene silencing by RNAi for development of therapeutics AbstractRNAi has been proposed as a therapeutic strategy for disorders characterized by aberrant gene overexpression (cancer, macular degeneration etc.) as well...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biologic, Gene therapy, Infectious disease, Research tool, RNA - Ribonucleic Acid, Therapeutics, Vector/Plasmid
Category(s): Life Sciences > Therapeutics
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HPS1 and HPS4 Function as RNAi Inhibitors: A Means to Boost RNAi for Experimental, Therapeutic & Commercial Purposes
NU 2005-063BInventorsRichard Carthew* Dinari Harris Young Sik Lee Short DescriptionNovel strategy to improve gene silencing by RNAi for development of therapeutics AbstractRNAi has been proposed as a therapeutic strategy for disorders characterized by aberrant gene overexpression (cancer, macular degeneration etc.) as well as for controlling viral infections....
Published: 11/6/2025
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Inventor(s):
Keywords(s): Assay, Biologic, Gene therapy, Therapeutics, Vector/Plasmid
Category(s): Life Sciences > Therapeutics
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Potential Treatment Of Corneal Vascularization
NU 2018-012
Inventors
Tsutomu Kume
Short Description
A gene therapy approach to diminish corneal vascularization
Background
Normally devoid of blood vessels, the cornea can become vulnerable to vascularization due to bacterial and viral infections, chemical injury, autoimmune conditions, and post-corneal transplantation, which can lead to...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Gene therapy, Ophthalmic disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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Gene Therapy for Major Depressive Disorder
NU 2016-039 InventorsDane Chetkovich* Ye Han Short DescriptionGene therapy for treating depressionBackgroundMajor depressive disorder (MDD), also known as clinical depression, is a highly prevalent public health problem that affects approximately 3% of the world's population. Although there are many drugs available to treat these patients, nearly all...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Gene therapy, Psychiatric disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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Sirt1 Gene Therapy For Improved Wound Healing
NU 2014-173 InventorsMichele JenGuillermo Ameer* Short DescriptionNovel gene therapy delivered from a hydrogel wound dressing (NanonetsTM) augments Sirt1 expression to improve wound healing BackgroundChronic wounds such as non-healing diabetic foot ulcers are a great challenge for the physician and contribute to increasing healthcare costs. Others have...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomedical, Gene therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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Novel Gene Delivery Using Self-Assembled Virus-Like Nanoparticles
NU 2011-123 InventorsYves RuffSamuel I. Stupp* Short DescriptionA method of making self-assembled nanostructures for improved gene and siRNA delivery.BackgroundThe use of peptides for the protection and delivery of nucleic acids is a well-established field. Molecular self-assembly has evolved in its capacity to design increasingly complex delivery structures...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Devices, Gene therapy, Health IT, Medical device, Nanoparticle
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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