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Northwestern Startup: Syenex, Inc.
Northwestern Inventor:
Joshua Leonard
McCormick School of Engineering
Chemical and Biological Engineering
Syenex builds bioengineering technologies to unlock the future of human health. Leveraging the power of synthetic biology, we design scalable, precision-engineered components, empowering cell and gene therapy developers to cure disease and build...
Published: 5/5/2026
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Updated: 5/5/2026
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Inventor(s):
Keywords(s): Biologic, Biomedical, Drug delivery, Gene therapy, Platform technology, Research tool, Startup with Northwestern IP, Synthetic biology, Therapeutics, Vector/Plasmid
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Therapeutics
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Novel 2-Imidazolyl-Pyrimidine Inhibitors for Neurodegenerative Disease Therapeutics
NU 2014-101
INVENTORS
Richard Silverman*
Paramita Mukherjee
SHORT DESCRIPTION
This invention introduces novel 2-imidazolyl-pyrimidine scaffolds that inhibit neuronal nitric oxide synthase. It offers potential for drug development targeting Parkinson’s and other neurodegenerative diseases.
BACKGROUND
Neurodegenerative disorders such as...
Published: 12/3/2025
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Updated: 11/18/2025
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Inventor(s):
Keywords(s): Biomedical, Materials, Neurodegenerative disease, Neurologic disease, Neurology, Small molecule, Therapeutics
Category(s): Physical Sciences > Materials and Industrial Processes
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Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 12/9/2025
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Updated: 10/30/2025
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Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Morphology Recurrence Analysis for the Characterization of Atrial Fibrillation Electrograms
INVENTORS
Jeffrey Goldberger*
David Gordon
Jason Ng
SHORT DESCRIPTION
This technique uses modified recurrence analysis on electrogram data to identify patient-specific arrhythmia drivers. It supports precise, tailored ablation mapping for atrial fibrillation.
BACKGROUND
Traditional atrial fibrillation mapping struggles with dynamic, variable...
Published: 12/9/2025
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Updated: 10/21/2025
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Inventor(s):
Keywords(s): Analysis, Biomedical, Cardiology and Cardiovascular disease, Computer software, Devices, Electrophysiology, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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A Novel Combination Therapy for Parkinson’s Disease
NU 2013-149
INVENTORS
Dalton Surmeier Jr. (Northwestern University, Feinberg School of Medicine, Chair of the Department of Neuroscience)*
Daniel Galtieri
Ema Ilijic
Enrico Zampese
Jaime Guzman-Lucero
Javier Sanchez
SHORT DESCRIPTION
This technology uses a low-dose combination of two FDA-approved compounds to reduce oxidative stress in neurons...
Published: 11/6/2025
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Updated: 10/9/2025
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Inventor(s):
Keywords(s): Biomedical, Drug delivery, Neurodegenerative disease, Neurologic disease, PD - Parkinson's Disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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Heparin Conjugated to Collagen-Binding Peptides for Targeting to Biological and Synthetic Tissues
NU 2017-175
INVENTORS
Guillermo Ameer*
Jason Wertheim*
Bin Jiang
Kyle Koss
SHORT DESCRIPTION
A synthetic form of heparin optimized to reduce blood coagulation by collagen stabilization.
BACKGROUND
Thrombosis, the local formation of blot clots, presents a major challenge to regenerative medicine procedures that utilize matrix scaffolds. Patients...
Published: 11/6/2025
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Updated: 10/2/2025
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Inventor(s):
Keywords(s): Biomedical, Devices, General surgery, Health IT, Materials, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Wireless, Miniaturized Sensing Platforms for Inflammatory Bowel Diseases
LUNU 2023-223
INVENTORS
John Rogers*
Arun Sharma*
Surabhi Madhvapathy
Matthew Bury
SHORT DESCRIPTION
Miniaturized, implantable temperature sensors for real-time, minimally invasive monitoring of inflammatory bowel diseases.
BACKGROUND
Inflammatory Bowel Disease (IBD), encompassing Crohn’s disease and ulcerative colitis, affects over 10...
Published: 12/22/2025
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Updated: 5/8/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Biomedical, Biotechnology, Devices, Diagnostics, Electronics & Circuits, Gastrointestinal and Hepatic disease, Healthcare, Medical device, Obesity, Sensors, Wireless
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Wireless, Implantable Catheter-type Oximeter Designed for Cardiac Oxygen Saturation
LUNU 2020-226
INVENTORS
John Rogers*
Wei Lu
Joseph Forbess
Zhi-Dong Ge
SHORT DESCRIPTION
This technology introduces a wireless, miniaturized, implantable catheter-type oximeter designed to offer real-time monitoring of intravascular oxygen levels for post-cardiothoracic surgery care.
BACKGROUND
Accurate, real-time monitoring of intravascular oxygen...
Published: 11/6/2025
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Updated: 5/7/2025
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Inventor(s):
Keywords(s): Biomedical, Cardiology and Cardiovascular disease, Devices, Diagnostics, Medical device, Optics, Sensors, Wireless
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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A microneedle-patterned polymer coating for next-generation drug-coated balloon catheters
NU 2024-188
Inventors
Bowen Wang*
Guojun Chen
Short Description
Next generation drug-coated balloon catheter using a microneedle-patterned polymer coating to penetrate deep into vessel walls and deliver a variety of payloads.
Background
Balloon angioplasty remains the standard of care for occlusive cardiovascular diseases, yet its...
Published: 11/6/2025
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Updated: 2/13/2025
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Inventor(s):
Keywords(s): Biomedical, Cardiology and Cardiovascular disease, Drug delivery, Healthcare, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Aesthetics and Wound Healing-related Technologies
NU2014-173; NU2014-168; NU2015-071; NU2015-101; NU2017-011; NU2018-151; NU2020-033; NU2020-249; NU2022-016; NU2022-079; NU2024-094
Transform your wound care and tissue repair solutions with our portfolio of technologies that provide cutting-edge solutions for wound care, tissue engineering, and disease treatment. This includes hydrogels that promote...
Published: 4/15/2026
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Updated: 9/6/2024
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Inventor(s):
Keywords(s): Adhesive, Biomedical, Biotechnology, General surgery, Hydrogel, Wound healing
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT
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