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Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 11/7/2025
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Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Morphology Recurrence Analysis for the Characterization of Atrial Fibrillation Electrograms
INVENTORS
Jeffrey Goldberger*
David Gordon
Jason Ng
SHORT DESCRIPTION
This technique uses modified recurrence analysis on electrogram data to identify patient-specific arrhythmia drivers. It supports precise, tailored ablation mapping for atrial fibrillation.
BACKGROUND
Traditional atrial fibrillation mapping struggles with dynamic, variable...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Analysis, Biomedical, Cardiology and Cardiovascular disease, Computer software, Devices, Electrophysiology, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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A Novel Combination Therapy for Parkinson’s Disease
NU 2013-149
INVENTORS
Dalton Surmeier Jr. (Northwestern University, Feinberg School of Medicine, Chair of the Department of Neuroscience)*
Daniel Galtieri
Ema Ilijic
Enrico Zampese
Jaime Guzman-Lucero
Javier Sanchez
SHORT DESCRIPTION
This technology uses a low-dose combination of two FDA-approved compounds to reduce oxidative stress in neurons...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomedical, Drug delivery, Neurodegenerative disease, Neurologic disease, PD - Parkinson's Disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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Heparin Conjugated to Collagen-Binding Peptides for Targeting to Biological and Synthetic Tissues
NU 2017-175
INVENTORS
Guillermo Ameer*
Jason Wertheim*
Bin Jiang
Kyle Koss
SHORT DESCRIPTION
A synthetic form of heparin optimized to reduce blood coagulation by collagen stabilization.
BACKGROUND
Thrombosis, the local formation of blot clots, presents a major challenge to regenerative medicine procedures that utilize matrix scaffolds. Patients...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomedical, Devices, General surgery, Health IT, Materials, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Wireless, Miniaturized Sensing Platforms for Inflammatory Bowel Diseases
LUNU 2023-223
INVENTORS
John Rogers*
Arun Sharma*
Surabhi Madhvapathy
Matthew Bury
SHORT DESCRIPTION
Miniaturized, implantable temperature sensors for real-time, minimally invasive monitoring of inflammatory bowel diseases.
BACKGROUND
Inflammatory Bowel Disease (IBD), encompassing Crohn’s disease and ulcerative colitis, affects over 10...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Biomedical, Biotechnology, Devices, Diagnostics, Electronics & Circuits, Gastrointestinal and Hepatic disease, Healthcare, Medical device, Obesity, Sensors, Wireless
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Wireless, Implantable Catheter-type Oximeter Designed for Cardiac Oxygen Saturation
LUNU 2020-226
INVENTORS
John Rogers*
Wei Lu
Joseph Forbess
Zhi-Dong Ge
SHORT DESCRIPTION
This technology introduces a wireless, miniaturized, implantable catheter-type oximeter designed to offer real-time monitoring of intravascular oxygen levels for post-cardiothoracic surgery care.
BACKGROUND
Accurate, real-time monitoring of intravascular oxygen...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomedical, Cardiology and Cardiovascular disease, Devices, Diagnostics, Medical device, Optics, Sensors, Wireless
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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A microneedle-patterned polymer coating for next-generation drug-coated balloon catheters
NU 2024-188
Inventors
Bowen Wang*
Guojun Chen
Short Description
Next generation drug-coated balloon catheter using a microneedle-patterned polymer coating to penetrate deep into vessel walls and deliver a variety of payloads.
Background
Balloon angioplasty remains the standard of care for occlusive cardiovascular diseases, yet its...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomedical, Cardiology and Cardiovascular disease, Drug delivery, Healthcare, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Aesthetics and Wound Healing-related Technologies
NU2014-173; NU2014-168; NU2015-071; NU2015-101; NU2017-011; NU2018-071; NU2018-151; NU2020-033; NU2020-249; NU2022-016; NU2022-079; NU2024-094
Transform your wound care and tissue repair solutions with our portfolio of technologies that provide cutting-edge solutions for wound care, tissue engineering, and disease treatment. This includes hydrogels...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Adhesive, Biomedical, Biotechnology, General surgery, Hydrogel, Wound Healing
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT
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Analytical Device for Sorting Single Cells Based on Secreted Products
NU 2023-084
INVENTORS
Shana O. Kelley*
Zongjie Wang
Mahmoud A. M. Labib
SHORT DESCRIPTION
A high-throughput, cost-effective device for sorting of single cells in a culture and analysis of their secreted products.
BACKGROUND
The demand for cost-effective cell analysis methods is expanding due to the increasing urge for the early detection,...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Biomedical, Devices, Diagnostics, Drug screening, Personalized medicine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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A novel preparation for ultra-small polymer-grafted nanobins for the targeted delivery of biomedicines
NU 2013-210
INVENTORS
SonBinh Nguyen*
Anthony Chipre
SHORT DESCRIPTION
A method of preparation to increase long-term stability and controlled release for ultra-small polymer-grafted nanobins
BACKGROUND
Small unilamellar vesicles (SUVs) are liposomes in 15 – 50 nm range. These components are of growing interest due to their small size, biocompatibility,...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomedical, Devices, Drug delivery, Gene therapy, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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