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Rapid Detection of an Anthrax Biomarker by Surface-Enhanced Raman Spectroscopy
NU 2006-092
Inventors
Richard Van Duyne*
Olga Lyandres
Matthew Young
Xiaoyu Zhang
Alyson Whitney
Jing Zhao
Jeffrey Elam
Short Description
Highly sensitive biosensor for detection of anthrax-causing bacterium with field use capabilities
Abstract
Northwestern researchers have created a surface-enhanced Raman biosensor for use in detecting...
Published: 4/15/2026
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Updated: 4/15/2026
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Inventor(s):
Keywords(s): Devices, Diagnostics, Health IT, Imaging, Medical device, Sensors
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Orthogonal Synthetic Receptors for IL-23
SHORT DESCRIPTION
Synthetic IL-23 receptors for cell engineering to enable real-time sensing and drive precise autoimmune and cancer immunotherapy interventions.
INVENTORS
Joshua Leonard*
McCormick School of Engineering, Department of Chemical and Biological Engineering
Aaron Morris
William Corcoran
...
Published: 5/8/2026
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Updated: 4/14/2026
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Inventor(s):
Keywords(s): Autoimmune disease, Cell engineering, Cell therapy, Diagnostics, IBD - Inflammatory bowel disease, Immunology, Immunotherapy, Inflammation, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools
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Responsive Probiotic Therapy for Local Detection and Treatment of IBD Flares
SHORT DESCRIPTION
An engineered probiotic that senses intestinal inflammation via calprotectin and locally releases therapeutic antibodies in the gastrointestinal tract only during inflammatory flares.
INVENTORS
Arthur Prindle*
McCormick School of Engineering, Department of Chemical and Biological Engineering
Jonathan...
Published: 5/11/2026
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Updated: 4/14/2026
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Inventor(s):
Keywords(s): Autoimmune disease, Biologic, Cell therapy, Diagnostics, Gastrointestinal and Hepatic disease, IBD - Inflammatory bowel disease, Immunology, Immunotherapy, Inflammation, Synthetic biology, Therapeutics
Category(s): Life Sciences > Therapeutics
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Extracellular vesicles for diagnosis and treatment of breast cancer
SHORT DESCRIPTION
Novel methods for detecting cancer through exosome analysis and bioengineered exosomes specifically designed to target cancer stem cells (CSCs).
INVENTORS
Huiping Liu*, MD, PhD
Associate Professor, Pharmacology, Medicine (Hematology and Oncology), Northwestern University Feinberg School...
Published: 2/6/2026
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Updated: 2/6/2026
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Inventor(s):
Keywords(s): Biomarker, Breast cancer, Cancer/Oncology, Diagnostics, Imaging, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Focal Adhesion Proteins as Non-Invasive Diagnostics for Podocytopathies
SHORT DESCRIPTION
A diagnostic technology that detects focal adhesion complex proteins in bodily fluids for rapid and non-invasive identification of podocytopathies.
INVENTORS
Lorenzo Gallon*, MD
Robert Gerbasi
* Principal Investigator
NU Tech ID: 2019-056
IP STATUS
US Patent Pending
DEVELOPMENT STAGE
TRL-3...
Published: 2/5/2026
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Updated: 1/30/2026
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Inventor(s):
Keywords(s): Biomarker, Diagnostics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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A Biological Marker for Concussion
NU 2016-016
INVENTORS
Nina Kraus*
Trent Nicol
Travis White-Schwoch
SHORT DESCRIPTION
This technology provides a method for objectively identifying non-penetrating brain injuries by analyzing the brain’s frequency following response (FFR) to an acoustic stimulus. It offers a non-invasive alternative that improves diagnostic precision and...
Published: 12/9/2025
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Updated: 11/7/2025
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Inventor(s):
Keywords(s): Biomarker, Brain injury, Devices, Diagnostics, Electrophysiology, Health IT, Medical device, Neurologic disease, Research tool
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 12/9/2025
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Updated: 10/30/2025
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Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Nanocytological and Molecular Analysis of Fecal Colonocytes for Colon Cancer Screening
NU 2010-131
INVENTORS
Vadim Backman*
Dhwanil Damania
Dhananjay Kunte
Hariharan Subramanian
Hemant Roy
Mart De La Cruz
SHORT DESCRIPTION
This technology offers a novel fecal test that detects nanoarchitectural and molecular markers in colonocytes. It delivers a minimally invasive screening method for early detection of colon cancer.
BACKGROUND
Colorectal...
Published: 12/9/2025
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Updated: 10/10/2025
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Inventor(s):
Keywords(s): Cancer/Oncology, Colon cancer, Diagnostics, Drug screening, Imaging, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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A NON-INVASIVE DIAGNOSTICS PLATFORM FOR MEASURING GLUCOSE LEVELS IN SALIVA
NU 2017-094
Inventors
Vinayak P. Dravid*
Vikas Nandwana
Short Description
A non-invasive diagnostic platform for detecting glucose in saliva.
Background
The glucometer is currently the state-of-the-art technology for at home glucose detection and is based on electrochemical analytics of blood samplings. Patients prick their finger and transfer...
Published: 5/6/2026
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Updated: 5/25/2025
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Inventor(s):
Keywords(s): Devices, Diabetes, Diagnostics, Health IT, Medical device
Category(s): Physical Sciences > Materials and Industrial Processes
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Wireless, Miniaturized Sensing Platforms for Inflammatory Bowel Diseases
LUNU 2023-223
INVENTORS
John Rogers*
Arun Sharma*
Surabhi Madhvapathy
Matthew Bury
SHORT DESCRIPTION
Miniaturized, implantable temperature sensors for real-time, minimally invasive monitoring of inflammatory bowel diseases.
BACKGROUND
Inflammatory Bowel Disease (IBD), encompassing Crohn’s disease and ulcerative colitis, affects over 10...
Published: 12/22/2025
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Updated: 5/8/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Biomedical, Biotechnology, Devices, Diagnostics, Electronics & Circuits, Gastrointestinal and Hepatic disease, Healthcare, Medical device, Obesity, Sensors, Wireless
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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