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A Biological Marker for Concussion
NU 2016-016
INVENTORS
Nina Kraus*
Trent Nicol
Travis White-Schwoch
SHORT DESCRIPTION
This technology provides a method for objectively identifying non-penetrating brain injuries by analyzing the brain’s frequency following response (FFR) to an acoustic stimulus. It offers a non-invasive alternative that improves diagnostic precision and...
Published: 11/7/2025
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Inventor(s):
Keywords(s): Biomarker, Brain injury, Devices, Diagnostics, Electrophysiology, Health IT, Medical device, Neurologic disease, Research tool
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 11/7/2025
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Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Therapy for non-alcoholic fatty liver disease
NU 2019-095
INVENTORS
Grant Barish*
Meredith Sommars
Madhavi Senagolage
SHORT DESCRIPTION
Targeting B cell lymphoma protein 6 (BCL6) with small molecule inhibitors as a therapeutic strategy for non-alcoholic fatty liver disease.
BACKGROUND
Obesity is widely prevalent and linked to multiple comorbidities
including metabolic dysfunction-associated...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomarker, Research tool
Category(s): Life Sciences > Therapeutics
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Biological Markers for Diagnosis of Diseases Associated with Major Depression
NU 2010-062, NU 2013-167, and NU 2013-168
PRIMARY INVENTOR
Eva Redei
SHORT DESCRIPTION
A diagnostic platform and method to accurately diagnose and predict treatment response in patients suffering from depression and post-traumatic stress disorder.
BACKGROUND
Psychiatric disorders, such as major depressive disorder (MDD) and post-traumatic stress...
Published: 11/11/2025
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Inventor(s):
Keywords(s): Biomarker, Diagnostics, Psychiatric disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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A method to stratify subtypes of T1 bladder cancer for targeted therapeutics
NU 2020-155
INVENTORS
Joshua Meeks*
A Gordon Robertson
Clarice S. Groeneveld
Aurélien de Reyniès
SHORT DESCRIPTION
Using next-generation sequencing to classify patient subtypes of bladder cancer for targeted T1 tumor therapies
BACKGROUND
T1 bladder cancers have the highest progression and recurrence rates of all non-muscle-invasive...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomarker, Cancer/Oncology, Personalized medicine, Urology
Category(s): Life Sciences > Therapeutics
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Low Energy Excitations and Emissions using Mechanically Interlocked Fluorophores
NU 2020-039
INVENTORS
J Fraser Stoddart*
Amine Garci
Yassine Beldjoudi
ABSTRACT
Collisional intermolecular interactions between excited states form short-lived dimers and complexes that lead to the emergence of excimer/exciplex emission of lower energy, a phenomenon which must be differentiated from the photoluminescence (PL) of the monomeric molecules....
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomarker, Electronics & Circuits, Sensors
Category(s): Physical Sciences > Materials and Industrial Processes
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Platelet Factor 4 as a Biomarker of Defective Lymphatics
NU 2020-158
INVENTORS
Guillermo Oliver*
Stanley Rockson
SHORT DESCRIPTION
A new biomarker for identifying lymphatic vasculature diseases
BACKGROUND
Lymphatic vasculature defects often result in disfiguring, disabling, and, occasionally, life-threatening outcomes. Diagnostic tools for all of the lymphatic disorders are relatively limited, relying...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Assay, Biomarker, Diagnostics, Obesity, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Non-Invasive Assay for Confirming Fertilization and Predicting Developmental Potential Of Embryo
NU 2010-048 InventorsAlison KinThomas O'Halloran*Teresa Woodruff*Miranda Lee BernhardtBetty KongEmily QueShort Description A simple assay to predict oocyte fertilization and embryo quality.AbstractNorthwestern researchers have developed a non-invasive, colorimetric assay for predicting embryo quality and oocyte fertilization. The assay relies on the...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomarker, Diagnostics, Obstetric/Gynecological, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Nanostructures for Diagnosis and Therapy of Alzheimer's Disease
NU 2009-169 Inventors Vinayak Dravid* Saurabh Sharma Kristen Viola William Klein* Short Description Novel magnetic nanostructures that recognize toxic beta-amyloid protein oligomers responsible for Alzheimer's disease progression Abstract Northwestern University researchers have developed a new magnetic nanostructure that can be used to detect and...
Published: 11/6/2025
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Inventor(s):
Keywords(s): AD - Alzheimer’s Disease, Biomarker, Devices, Diagnostics, Health IT, Medical device, Nanoparticle, Neurodegenerative disease, Neurologic disease, Research tool, Therapeutics
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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MIP-1a (alpha) and MCP-1: Biomarkers For Chronic Pelvic Pain Syndrome
NU 2004-026InventorsAlisa KochAnthoy Schaeffer*AbstractNorthwestern researchers identified MIP-1a and MCP-1 as biomarkers for Chronic Pelvic Pain Syndrome (CPPS). These markers are easily assayed from expressed prostatic secretions. These are the first biomarkers that are able to diagnose both inflammatory (Type IIIa) and non-inflammatory (Type IIIb)...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomarker, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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