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Biomolecular Condensates as Protein Degradation Tools for Intracellular Targets
SHORT DESCRIPTION
A targeted-protein degradation platform for intracellular targets, addressing resistant oncogenic and neurodegenerative targets.
INVENTORS
Shana Kelley*
Weinberg College of Arts & Sciences, Department of Chemistry
Yi Li
* Principal Investigator
NU 2025-050
IP STATUS
PCT...
Published: 4/27/2026
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Updated: 4/27/2026
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Inventor(s):
Keywords(s): AD - Alzheimer’s Disease, Biologic, Biomolecular condensates, Cancer/Oncology, Drug delivery, Nanoparticle, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Platform technology, Targeted protein degradation, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools
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Smart Memtransistors: Learning to Forget On Demand
NU 2021-179
PRIMARY INVENTOR
Jiangtan Yuan
Stephanie Elizabeth Liu
Vinod Kumar Sangwan
Amit R. Trivedi
Mark C. Hersam*
SHORT DESCRIPTION
A reconfigurable memtransistor that can dynamically adapt to new learning tasks
BACKGROUND
Recent AI advances have been possible due to GPU enabled parallel computing. However, this high computing capacity is not...
Published: 11/6/2025
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Updated: 12/17/2021
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Inventor(s):
Keywords(s): Artificial Intelligence & Machine Learning, Computer hardware, Data processing/analysis, Data storage, Electronics & Circuits, Nanotechnology, Platform technology, Quantum computing, Semiconductors & Integrated Circuits
Category(s): Physical Sciences > Materials and Industrial Processes, Physical Sciences > Engineering & Technology
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Megamolecule Synthetic Antibodies
NU 2016-048
Inventors
Milan Mrksich*
Justin Modica
Short Description
A novel method to join antibody fragments to produce megamolecule antibody-like drugs
Abstract
Northwestern researchers have developed a novel Lego-like platform to build megamolecule antibodies whose fragments can be customized for particular targets. The development...
Published: 4/8/2026
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Updated: 10/27/2018
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Inventor(s):
Keywords(s): Antibody, Biologic, Platform technology, Therapeutics
Category(s): Life Sciences > Therapeutics
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