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Self-powered, bioresorbable drug release systems
NU 2023-045
INVENTORS
John Rogers*
Colin Franz*
Yamin Zhang
SHORT DESCRIPTION
Northwestern and Shirley Ryan AbilityLab researchers have developed a novel, self-powered, bioresorbable drug delivery system that enables light-controlled, targeted drug release without the need for surgical removal post-treatment.
BACKGROUND
Current drug delivery systems...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomaterials, Cancer/Oncology, Drug delivery, Infectious disease, Medical device, Therapeutics
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Sliding Bioactive Peptides for Therapeutic Delivery
NU 2023-142
INVENTORS
Samuel I. Stupp*
Federico Lancia
Madison E. Strong
Matias A. Alvarez-Saavedra
SHORT DESCRIPTION
This technology involves the design and engineering of peptide amphiphile nanofibers that deliver bioactive peptides both extra- and intra-cellularly. The bioactive peptides can slide along these structures...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomaterials, Drug delivery
Category(s): Life Sciences > Therapeutics
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Ion-Doped Supramolecular Nanostructures
NU 2023-006
INVENTORS
Samuel Stupp*
Zaida Alvarez Pinto
Ivan Ramos Sasselli
Nicholas Allen Sather
Zois Syrgiannis
SHORT DESCRIPTION
This technology involves the development of ion-doped peptide amphiphiles (IDPAs) that form supramolecular nanostructures capable of enhancing neural development and membrane excitability...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomaterials, Drug delivery, Nanomaterials
Category(s): Physical Sciences > Materials and Industrial Processes
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Peptide Amphiphiles for Sonic Hedgehog Regulation of Pelvic Nerves for Treatment of Stress Urinary Incontinence and Erectile Dysfunction
NU 2018-075, 2018-076, 2018-077
INVENTORS
Caroline Podlasek
Kevin McVary
Daniel Harrington
Samuel Stupp*
SHORT DESCRIPTION
Novel peptide amphiphile (PA) nanofiber hydrogel is used to deliver sonic hedgehog (SHH) protein to nerves of the major pelvic ganglia and the rhabdospincter as a treatment for erectile dysfunction and urinary incontinence.
...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomaterials, Drug delivery, Materials, Therapeutics
Category(s): Life Sciences > Therapeutics
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Aqueous Peptide Programming of Organic Ferroelectric Materials
NU2023-005
INVENTORS
Samuel Stupp*
Yang Yang
SHORT DESCRIPTION
Novel peptide material with precise nanoscale assembly, versatility in morphology, enhanced ferroelectric properties, high-temperature and electrochemical performance.
BACKGROUND
Poly(vinylidene fluoride) (PVDF) is the leading organic ferroelectric material with multiaxial ferroelectricity,...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomaterials, Materials
Category(s): Physical Sciences > Materials and Industrial Processes
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Nanopatterning for control of cell cytoskeleton
NU 2018-027
INVENTORS
Chad Mirkin*
Milan Mrksich*
Brian Meckes
Maria Cabezas
SHORT DESCRIPTION
Polymer pen lithography (PPL) to spatially define locations where cells can adhere to a substrate in aniosotropic patterns.
BACKGROUND
Cells have unique shapes that play significant roles in their function; cell shape influences cellular processes...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomaterials, Therapeutics
Category(s): Life Sciences > Therapeutics
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Novel Delivery System for BMP4 for the Treatment of Pediatric High-Grade Glioma
NU 2020-051
INVENTORS
Samuel I. Stupp
SHORT DESCRIPTION
A novel delivery system for bone morphogenetic protein 4 utilizing nanotechnology.
BACKGROUND
Pediatric high-grade glioma (HGG) is among the most formidable cancer occurring in childhood patients. Current treatments include surgery followed by chemo- and radiation therapy but, these have...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomaterials, Cancer/Oncology, Drug delivery, Drug delivery, Nanomaterials
Category(s): Life Sciences > Therapeutics
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Conducting Polymer Allograft Tissue Composites for Regeneration
NU 2020-004
INVENTORS
Jonathan Rivnay*
Anthony Petty II
Erin Hsu
SHORT DESCRIPTION
A biomimetic electroactive biomaterial for tissue regeneration
ABSTRACT
Incorporating electroactive components in biomaterials has a significant effect on cellular adhesion, proliferation, and differentiation, as well as allowing for both the possibility of...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomaterials, Biomedical, Electronics & Circuits, Polymer, Smart/Functional materials
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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