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Wireless, Miniaturized Sensing Platforms for Inflammatory Bowel Diseases
LUNU 2023-223
INVENTORS
John Rogers*
Arun Sharma*
Surabhi Madhvapathy
Matthew Bury
SHORT DESCRIPTION
Miniaturized, implantable temperature sensors for real-time, minimally invasive monitoring of inflammatory bowel diseases.
BACKGROUND
Inflammatory Bowel Disease (IBD), encompassing Crohn’s disease and ulcerative colitis, affects over 10...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Biomedical, Biotechnology, Devices, Diagnostics, Electronics & Circuits, Gastrointestinal and Hepatic disease, Healthcare, Medical device, Obesity, Sensors, Wireless
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Analytical Device for Sorting Single Cells Based on Secreted Products
NU 2023-084
INVENTORS
Shana O. Kelley*
Zongjie Wang
Mahmoud A. M. Labib
SHORT DESCRIPTION
A high-throughput, cost-effective device for sorting of single cells in a culture and analysis of their secreted products.
BACKGROUND
The demand for cost-effective cell analysis methods is expanding due to the increasing urge for the early detection,...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Biomedical, Devices, Diagnostics, Drug screening, Personalized medicine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Immunomodulatory Nanoparticles for the Therapeutic Intervention of Traumatic Brain Injury
NU 2019-030
INVENTORS
John Kessler
Sripadh Sharma
ABSTRACT
There is no decisive treatment for traumatic brain injury (TBI). After the primary trauma, secondary injury, largely mediated by blood-borne immune cells called monocytes, takes place causing damage to surrounding healthy cells. Furthermore, cellular and whole brain swelling (edema) resulting...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Brain injury, CNS - Central Nervous System, Immunology, Neurology, Therapeutics
Category(s): Life Sciences > Therapeutics
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POP3, a Novel Inflammasome Inhibitor and its Use Of
NU 2010-160 Inventors Christian Stehlik Short DescriptionPOP3 protein as a method to modulate inflammationAbstract Northwestern researchers have identified a new member of the PYD-only protein (POPs) family (POP3) as a specific regulator of ALR inflammasomes, promoting IFN-beta production and reducing IL-1beta and IL-8 production. POP3 has the potential...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Infectious disease, Inflammation, Therapeutics
Category(s): Life Sciences > Therapeutics
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Targeted Enhancement of CD154 Trimer Stability for Modulation of Immune Function
NU 2005-008 InventorsLaurence Howard John Irwin Stephen Miller* Brian Shoichet AbstractRegulating immune cell response is critical in combating disease. Northwestern researchers have developed a new therapy that can either inhibit immune cell function in autoimmune disease or enhance natural or vaccine-facilitated immune responses. A small molecule...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Cancer/Oncology, Immunology, Infectious disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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