|
Use of interferon-gamma antibody to reduce damage to the heart after myocardial infarction
NU 2024-243
INVENTORS
Hossein Ardehali*
Sam E. Weinberg
Amir Mahmoodzadeh
SHORT DESCRIPTION
Interferon-gamma antibodies to improve heart function after myocardial infarction (MI)
BACKGROUND
Myocardial infarction (MI) can trigger inflammation that contributes to adverse cardiac remodeling, which increases the risk of heart failure and...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): Antibody, Cardio-Pulmonary
Category(s): Life Sciences > Therapeutics
|
|
Humanized antibody targeting the tumor associated antigen, IL13Ra2
Humanized antibody targeting the tumor associated antigen, IL13Ra2
NU 2020-031
INVENTORS
Irina Balyasnikova*
SHORT DESCRIPTION
A novel antibody that specifically targets glioblastoma cells
BACKGROUND
Glioblastoma is a deadly, incurable disease with a low 5 year survival rate. The current standard of care typically involves surgical resection...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): Antibody, Cancer/Oncology, CAR T, Cell therapy, Gene therapy, Neurologic disease, Personalized medicine, Research tool, Therapeutics
Category(s): Life Sciences > Therapeutics
|
|
Antibodies Against Transcription Factors BMAL1 and CLOCK for the Study of Metabolic Disease
NU 2015-059INVENTORSJoseph T. Bass*Clara Bien PeekGrant D. Barish SHORT DESCRIPTIONAntibodies targeting transcription factors, BMAL1 and CLOCK, to study the regulation of circadian expression of proteins related to metabolic diseaseBACKGROUNDMetabolic diseases such as diabetes, obesity, and related diseases such as inflammation and cancer affect millions...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): Antibody, Diabetes, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Immunotherapy for Treating Age-Related Macular Degeneration
NU 2007-161B InventorsArthur Neufeld* Ai Ling WangAbstractDeposition of drusen, accumulations of extracellular material, in the macula is a key factor in the etiology of Age-related Macular Degeneration (AMD). Northwestern researchers have identified compounds for the treatment and prevention of drusen. The researchers use an immunotherapeutic approach,...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): Antibody, Ophthalmic disease, Therapeutics
Category(s): Life Sciences > Therapeutics
|
|
Novel Risk Prediction and Diagnosis of Type 1 Diabetes using Deamidated Proinsulin
NU 2014-193 INVENTORXunrong LuoJing Jin*Grazia Aleppo-KacmarekSHORT DESCRIPTIONA diagnostic method to detect autoantibody reactivity for deamidated insulin in diabetes BACKGROUNDType 1 diabetes (T1D) is classified as an autoimmune disease. In this disease, the immune system mounts misguided destruction of “self” insulin-producing islet...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): Antibody, Diabetes, Diagnostics, Imaging, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Tau-7: Monoclonal Antibody Specific for the C-Terminus of Tau
NU 2008-109InventorLester BinderShort DescriptionTau-7 is a mouse monoclonal antibody (mAb) that binds to the carboxy terminal region of human tau. AbstractResearcher Lester Binder has created a series of useful antibodies that are specific for the human tau protein. This particular antibody, Tau-7 mAb, is of the IgG1 isotype and would be useful to...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): AD - Alzheimer’s Disease, Antibody, Diagnostics, Imaging, Neurodegenerative disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Antibodies against Heat Shock Factors (HSF1 and HSF2)
NU 1996-097InventorsJose Cotto*Richard I. MorimotoBackgroundHeat shock proteins and molecular chaperones are involved in many cellular metabolic processes including protein synthesis, folding/assembly, membrane translocation and degradation in normally growing cells. Under stress conditions, abnormal proteins increase and rapid and transient activation...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): Antibody, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Tau-13: Monoclonal Antibody to Tau
NU 2000-081 InventorLester Binder Short DescriptionTau-13 is a mouse monoclonal antibody (mAb) that binds to human tau. AbstractResearcher Lester Binder has created a series of useful antibodies that are specific for the human tau protein. This particular antibody, Tau-13 mAb, is of the IgG1 subtype and would be useful to researchers who wish to detect...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): Antibody, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Antibody Against THAP11 (#976) for Research
NU 2012-153 Inventors Debabrata Chakravarti* John Brandon Parker Santanu Palchaudhuri Abstract Thanatos-associated protein (THAP) contains an atypical zinc finger motif with sequence-specific DNA-binding activity. Emerging data suggest that THAP proteins may function in chromatin-dependent processes, including transcriptional regulation. The roles...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): Antibody, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Antibody Against THAP11 (#E1676) for Research
NU 2012-152 Inventors Debabrata Chakravarti* John Brandon Parker Santanu Palchaudhuri Abstract Thanatos-associated protein (THAP) contains an atypical zinc finger motif with sequence-specific DNA-binding activity. Emerging data suggest that THAP proteins may function in chromatin-dependent processes, including transcriptional regulation. The roles...
Published: 11/6/2025
|
Inventor(s):
Keywords(s): Antibody, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|