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Engineered Lipid Tags for Extracellular Vesicle Loading
NU 2022-178
INVENTORS
Neha Kamat*
Joshua Leonard*
Justin Alexander Peruzzi
Taylor Gunnels
SHORT DESCRIPTION
This technology enhances the loading of protein cargo into extracellular vesicles (EVs) by directing protein association with membrane lipid rafts, utilizing engineered lipid tags for targeted delivery.
BACKGROUND
Extracellular...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biotechnology, Drug delivery, Nanoparticle, Synthetic biology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Leveraging Lipid-Protein Interactions to Engineer Spatial Organization in Cell-free Systems
NU 2021-231
INVENTORS
Neha Kamat*
Justin Alexander Peruzzi
Jan Steinkuehler
SHORT DESCRIPTION
This innovative method enables the control of membrane protein location and distribution in synthetic lipid membranes using lipid-protein interactions, without chemical conjugation, facilitating the development of advanced cell-free systems.
BACKGROUND
Spatially...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biotechnology, Drug delivery, Nanoparticle, Synthetic biology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Physical Sciences > Engineering & Technology
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Modular Extracellular Sensors for Cell-based Biosensors
NU 2011-109BInventorsJoshua Leonard*Rachel Dudek Nichole Daringer Short DescriptionEngineered receptors designed to control gene expression BackgroundEngineering mammalian cell-based devices that monitor and therapeutically modulate human physiology is a promising and emerging frontier in clinical synthetic biology. However, realizing this vision required...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Animal Model, Diagnostics, Research tool, Sensors, Synthetic biology, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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