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Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 11/7/2025
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Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Analytical Device for Sorting Single Cells Based on Secreted Products
NU 2023-084
INVENTORS
Shana O. Kelley*
Zongjie Wang
Mahmoud A. M. Labib
SHORT DESCRIPTION
A high-throughput, cost-effective device for sorting of single cells in a culture and analysis of their secreted products.
BACKGROUND
The demand for cost-effective cell analysis methods is expanding due to the increasing urge for the early detection,...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Autoimmune disease, Biomedical, Devices, Diagnostics, Drug screening, Personalized medicine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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A method to stratify subtypes of T1 bladder cancer for targeted therapeutics
NU 2020-155
INVENTORS
Joshua Meeks*
A Gordon Robertson
Clarice S. Groeneveld
Aurélien de Reyniès
SHORT DESCRIPTION
Using next-generation sequencing to classify patient subtypes of bladder cancer for targeted T1 tumor therapies
BACKGROUND
T1 bladder cancers have the highest progression and recurrence rates of all non-muscle-invasive...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomarker, Cancer/Oncology, Personalized medicine, Urology
Category(s): Life Sciences > Therapeutics
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Exercise Induced Myokines to Target Receptor Kinases and Chromatin Architecture
NU 2019-094
INVENTORS
Vadim Backman*
Hemant K. Roy
SHORT DESCRIPTION
Novel oncology drug discovery platform using contraction-induced myokine secretion
BACKGROUND
Colorectal cancer is the third most commonly diagnosed cancer and second most common cause of cancer deaths in the United States. Despite its frequency, there are limited treatment...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cancer/Oncology, Drug discovery, Personalized medicine
Category(s): Life Sciences > Therapeutics
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Humanized antibody targeting the tumor associated antigen, IL13Ra2
Humanized antibody targeting the tumor associated antigen, IL13Ra2
NU 2020-031
INVENTORS
Irina Balyasnikova*
SHORT DESCRIPTION
A novel antibody that specifically targets glioblastoma cells
BACKGROUND
Glioblastoma is a deadly, incurable disease with a low 5 year survival rate. The current standard of care typically involves surgical resection...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Antibody, Cancer/Oncology, CAR T, Cell therapy, Gene therapy, Neurologic disease, Personalized medicine, Research tool, Therapeutics
Category(s): Life Sciences > Therapeutics
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