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Closed-Loop Implantable System for Automated Opioid Overdose Detection and Reversal
NU 2019-073
INVENTORS
John Rogers (Northwestern University)*
Robert Gereau (Washington University, St Louis)*
SHORT DESCRIPTION
This wireless device, the size of a pacemaker, is implanted to monitor oxygen levels. Below a specific threshold, it sends an alert to warning notification on a mobile app, then automatically releases naloxone to prevent...
Published: 11/7/2025
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Inventor(s):
Keywords(s): Drug delivery, Electronics & Circuits, Medical device, Microfluidics
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Therapeutics
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A Biological Marker for Concussion
NU 2016-016
INVENTORS
Nina Kraus*
Trent Nicol
Travis White-Schwoch
SHORT DESCRIPTION
This technology provides a method for objectively identifying non-penetrating brain injuries by analyzing the brain’s frequency following response (FFR) to an acoustic stimulus. It offers a non-invasive alternative that improves diagnostic precision and...
Published: 11/7/2025
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Inventor(s):
Keywords(s): Biomarker, Brain injury, Devices, Diagnostics, Electrophysiology, Health IT, Medical device, Neurologic disease, Research tool
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Morphology Recurrence Analysis for the Characterization of Atrial Fibrillation Electrograms
INVENTORS
Jeffrey Goldberger*
David Gordon
Jason Ng
SHORT DESCRIPTION
This technique uses modified recurrence analysis on electrogram data to identify patient-specific arrhythmia drivers. It supports precise, tailored ablation mapping for atrial fibrillation.
BACKGROUND
Traditional atrial fibrillation mapping struggles with dynamic, variable...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Analysis, Biomedical, Cardiology and Cardiovascular disease, Computer software, Devices, Electrophysiology, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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BDNF Mimetic Peptide Amphiphile for Enhanced Neurotrophic Signaling and Neuronal Regeneration
NU 2018-020
INVENTORS
Samuel Stupp
Alexandra Kolberg
Zaida Alvarez Pinto
SHORT DESCRIPTION
This technology is an injectable, highly potent peptide amphiphile that mimics BDNF function via the TrkB pathway while providing extracellular support. It promotes neuronal growth and signaling for regenerative treatments in CNS injuries and diseases.
BACKGROUND
Current...
Published: 11/6/2025
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Inventor(s):
Keywords(s): CNS - Central Nervous System, Devices, Drug delivery, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Heparin Conjugated to Collagen-Binding Peptides for Targeting to Biological and Synthetic Tissues
NU 2017-175
INVENTORS
Guillermo Ameer*
Jason Wertheim*
Bin Jiang
Kyle Koss
SHORT DESCRIPTION
A synthetic form of heparin optimized to reduce blood coagulation by collagen stabilization.
BACKGROUND
Thrombosis, the local formation of blot clots, presents a major challenge to regenerative medicine procedures that utilize matrix scaffolds. Patients...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomedical, Devices, General surgery, Health IT, Materials, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Method, system, and apparatus of metabolic optical coherence tomography
NU 2013-083
INVENTORS
Vadim Backman*
Hao Zhang
Ji Yi
Wenzhong Liu
SHORT DESCRIPTION
A novel system employing dual-band coherence tomography, this invention quantitatively images tissue metabolism by measuring blood oxygen saturation and flow in vivo.
BACKGROUND
Optical Coherence Tomography (OCT) is a cornerstone non-invasive imaging modality...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Devices, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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A NON-INVASIVE DIAGNOSTICS PLATFORM FOR MEASURING GLUCOSE LEVELS IN SALIVA
NU 2017-094
Inventors
Vinayak P. Dravid*
Vikas Nandwana
Short Description
A non-invasive diagnostic platform for detecting glucose in saliva.
Background
The glucometer is currently the state-of-the-art technology for at home glucose detection and is based on electrochemical analytics of blood samplings. Patients prick their finger and transfer...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Devices, Diabetes, Diagnostics, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Intraoperative Neuromuscular Monitoring via Soft, Skin-Mounted Wireless Devices
NU 2017-108
INVENTORS
John Rogers*
SHORT DESCRIPTION
This technology introduces a soft, wireless, skin-mounted device that enables non-invasive, real-time monitoring of neuromuscular function during surgical procedures, reducing patient discomfort and procedural complexity.
BACKGROUND
Conventional intraoperative neuromuscular monitoring relies...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Devices, Health IT, Medical device, Neurology
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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A Smart, Compression Stocking Device
NU 2017-066
INVENTORS
John Rogers*
In Hwa Jung
Shuai Xu
SHORT DESCRIPTION
A smart compression stocking integrating flexible electronic sensors that provide real-time feedback on therapeutic pressure, ensuring optimal compression and improved patient adherence.
BACKGROUND
Medical compression stockings are widely used to manage venous stasis...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Consumer product, Devices, Engineering, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Self-powered, bioresorbable drug release systems
NU 2023-045
INVENTORS
John Rogers*
Colin Franz*
Yamin Zhang
SHORT DESCRIPTION
Northwestern and Shirley Ryan AbilityLab researchers have developed a novel, self-powered, bioresorbable drug delivery system that enables light-controlled, targeted drug release without the need for surgical removal post-treatment.
BACKGROUND
Current drug delivery systems...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Biomaterials, Cancer/Oncology, Drug delivery, Infectious disease, Medical device, Therapeutics
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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