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Inhibitors of TRIP8b for Novel Mood Disorder Therapeutics
SHORT DESCRIPTION For mood disorder treatment, these novel inhibitors disrupt TRIP8b-HCN binding to offer an alternative antidepressant mechanism.
INVENTORS
Gary Schiltz*
Weinberg College of Arts and Sciences, Department of Chemistry
Dane Chetkovich
Ye Han
Iredia Iyamu
Kyle Lyman
* Principal...
Published: 4/27/2026
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Updated: 4/27/2026
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Inventor(s):
Keywords(s): Antidepressant, Depression, Mood disorder, Neurologic disease, Neurology, Psychiatric disease, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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A CSF-derived therapy for psychiatric disorders
NU2023-196
INVENTORS
Peter Penzes*
Marc Dos Santos
BACKGROUND
Currently, there is a lack of treatments which address the negative and cognitive symptoms of psychiatric disorders such as schizophrenia. Northwestern researchers have designed a recombinant form of ⍺2d-1 protein, a subunit of the voltage-gated calcium channel, to restore protein...
Published: 4/14/2026
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Updated: 10/17/2024
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Inventor(s):
Keywords(s): ASD - Autism Spectrum Disorder, Biologic, Neurologic disease, Neurology, PSD - Psychotic spectrum disorder, Psychiatric disease, Schizophrenia, Therapeutics
Category(s): Life Sciences > Therapeutics
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Biological Markers for Diagnosis of Diseases Associated with Major Depression
NU 2010-062, NU 2013-167, and NU 2013-168
PRIMARY INVENTOR
Eva Redei
SHORT DESCRIPTION
A diagnostic platform and method to accurately diagnose and predict treatment response in patients suffering from depression and post-traumatic stress disorder.
BACKGROUND
Psychiatric disorders, such as major depressive disorder (MDD) and post-traumatic stress...
Published: 11/11/2025
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Updated: 7/5/2023
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Inventor(s):
Keywords(s): Biomarker, Diagnostics, Psychiatric disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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