Search Results - metabolic+disorders

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Small molecule inhibits the interaction between tristetraprolin and CNOT1 for therapeutic use in metabolic disorders

NU 2024-057 INVENTORS Hossein Ardehali* Jason Shapiro SHORT DESCRIPTION Compound that inhibits the interaction between tristetraprolin (TTP) and CCR4-NOT Transcription Complex Subunit 1 (CNOT1) offers potential therapeutic avenue for metabolic disorders by modulating mRNA degradation without inflammatory side effects. BACKGROUND Metabolic disorders...

Published: 3/26/2026 | Updated: 5/5/2025 | Inventor(s):

Keywords(s): Cardiology and Cardiovascular disease, Diabetes, Metabolic disorders, Small molecule, Therapeutics

Category(s): Life Sciences > Therapeutics

Antibodies Against Transcription Factors BMAL1 and CLOCK for the Study of Metabolic Disease

NU 2015-059INVENTORSJoseph T. Bass*Clara Bien PeekGrant D. Barish SHORT DESCRIPTIONAntibodies targeting transcription factors, BMAL1 and CLOCK, to study the regulation of circadian expression of proteins related to metabolic diseaseBACKGROUNDMetabolic diseases such as diabetes, obesity, and related diseases such as inflammation and cancer affect millions...

Published: 3/19/2026 | Updated: 4/24/2020 | Inventor(s):

Keywords(s): Antibody, Diabetes, Metabolic disorders, Research tool

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools