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Personalized chest acceleration derived prediction of cardiovascular abnormalities using deep learning
Personalized chest acceleration derived prediction of cardiovascular abnormailities using deep learning
NU 2023-121
INVENTORS
Michael Markl *
Ethan M.I. Johnson
Mahmoud Ebrahimkhani
SHORT DESCRIPTION
A system and method for predicting cardiovascular function using machine learning from physiological patient data.
BACKGROUND
Cardiac and flow...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Artificial Intelligence & Machine Learning, Cardiology and Cardiovascular disease, Cardio-Pulmonary, Computer hardware, Devices, Diagnostics, Imaging, Mobile networking, Networking
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Cardio VIBES: Quick Screening Tool for Cardiac Conditions using Vibrational Energy Spectral Heat Maps
NU 2020-174
INVENTORS
Michael Markl *
Ethan M.I. Johnson
SHORT DESCRIPTION
This technology offers a non-invasive, quick screening tool for detecting heart valve, cardiovascular, and cardiothoracic abnormalities using vibrational energy spectral (VIBES) heat maps.
BACKGROUND
Cardiac and flow abnormalities can often go undetected until serious...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cardiology and Cardiovascular disease, Cardio-Pulmonary
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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AI-Driven 3D Detection and Treatment of Atrial Fibrillation
2024-092, 2023-222, 2020-103
INVENTORS
Markus Rottmann*
SHORT DESCRIPTION
This technology introduces an innovative AI-driven system for precise detection and treatment of atrial fibrillation (AF) through advanced 3D mapping and bipolar ablation.
BACKGROUND
Atrial Fibrillation (AF) is an irregular rapid heart rhythm and the most common heart disorder,...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cardio-Pulmonary
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Use of interferon-gamma antibody to reduce damage to the heart after myocardial infarction
NU 2024-243
INVENTORS
Hossein Ardehali*
Sam E. Weinberg
Amir Mahmoodzadeh
SHORT DESCRIPTION
Interferon-gamma antibodies to improve heart function after myocardial infarction (MI)
BACKGROUND
Myocardial infarction (MI) can trigger inflammation that contributes to adverse cardiac remodeling, which increases the risk of heart failure and...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Antibody, Cardio-Pulmonary
Category(s): Life Sciences > Therapeutics
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Complement detection and inhibition improves lung transplant outcomes
NU 2023-199
INVENTORS
Ankit Bharat*
BACKGROUND
Lung transplants can often lead to dreaded complications shortly after transplantation. For example, the potentially lethal syndrome Primary Graft Dysfunction (PGD) manifests in more than 50% of recipients within the initial 72 hours after implantation and can lead to both short- and long-term...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cardio-Pulmonary, Organ transplantation
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Revolutionizing Lung Transplantation - A Comprehensive Approach to Combatting Primary Graft Dysfunction
NU 2022-147
INVENTOR
Ankit Bharat*
Emilia Lecuona
Wenbin Yang
BACKGROUND
Primary graft dysfunction (PGD) is a critical barrier to successful lung transplantation. Our research identifies pre-existing lung autoantibodies as key contributors to PGD, opening new avenues for prevention and treatment. We propose a streamlined tri-fold approach...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cardio-Pulmonary, Organ transplantation
Category(s): Life Sciences > Therapeutics
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A new therapeutic approach for treating and reversing heart failure with preserved ejection fraction
NU 2022-216
INVENTORS
Hossein Ardehali*
Yuki Tatekoshi
SHORT DESCRIPTION
A small-molecule inhibitor for treating, preventing, and reversing heart failure with preserved ejection fraction (HFpEF).
ABSTRACT
HFpEF is a common cause of mortality worldwide, but the underlying pathophysiology is not well understood and treatment options are limited....
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cardiology and Cardiovascular disease, Cardio-Pulmonary
Category(s): Life Sciences > Therapeutics
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Novel Biomarker for Lung Disease Diagnosis and Monitoring
NU2022-232
INVENTORS
Ankit Bharat*
Yuanqing Yan
SHORT DESCRIPTION
A robust and reliable biomarker for diagnosing and predicting lung disease
ABSTRACT
The lack of robust biomarkers for lung diseases is a pressing challenge. A team of scientists at Northwestern University has identified the protein serine protease inhibitor Kazal-type 1 (SPINK1)...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cardio-Pulmonary, Diagnostics, Lung disease
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Novel Therapeutic Target for Treating Lung Disease
NU2022-231
INVENTORS
Ankit Bharat*
Yuanqing Yan
SHORT DESCRIPTION
A novel protein target for treating chronic and acute lung diseases
ABSTRACT
Lung diseases caused by pulmonary fibrosis can be fatal, and the currently approved drugs for treating pulmonary fibrosis, including Nintedanib and Pirfenidone, only slow down the disease progression....
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cardio-Pulmonary, Lung disease
Category(s): Life Sciences > Therapeutics
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New Targets and Methods for Treating Pulmonary Hypertension and Cardiomyopathy
LU 2020-120, LU 2021-119, LU 2021-191
INVENTOR
Youyang Zhao*
SHORT DESCRIPTION
New targets and methods for treating pulmonary hypertension, cardiomyopathy, and heart failure.
BACKGROUND
Pulmonary hypertension (PH) and cardiomyopathy are deleterious diseases often characterized by excessive vasoconstriction or abnormal vascular-ventricular...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cancer/Oncology, Cardiology and Cardiovascular disease, Cardio-Pulmonary, Pulmonary disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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