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Methods for Treatment of Sepsis and Acute Respiratory Distress Syndrome
LU2025-192
INVENTORS
Youyang Zhao
Colin Evans
SHORT DESCRIPTION
This invention identifies endothelial ALOX15 and its lipid product, 1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol (POLAR), as key targets for treating sepsis and acute respiratory distress syndrome (ARDS).
BACKGROUND
Sepsis-induced acute lung injury (ALI) and acute...
Published: 12/11/2025
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Inventor(s):
Keywords(s): ARDS - Acute Respiratory Distress Syndrome, Lung disease, Sepsis, Therapeutics, Vascular disease, Vascular repair
Category(s): Life Sciences > Therapeutics
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