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Deep learning for automated, motion-resolved tumor segmentation in radiotherapy
NU2025-264 INVENTORS Mohamed Abazeed* Sagnik Sarkar Peng Thian Troy Teo SHORT DESCRIPTION This invention describes a method for automatically outlining lung tumors for radiotherapy planning. It uses deep learning to precisely identify tumors across breathing cycles, improving accuracy and reducing manual effort. BACKGROUND Accurate tumor...
Published: 2/17/2026   |   Inventor(s):  
Keywords(s): Artificial Intelligence & Machine Learning, Cancer/Oncology, Diagnostics, Imaging, Lung cancer, Radiotherapy
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Soft, Bioresorbable, Evaporative Microfluidic Coolers for Reversible Conduction Block of Peripheral Nerves
NU 2021-164 INVENTORS John Rogers* Jonathan Reeder Matthew MacEwan [Washington University, St Louis] Wilson Ray [Washington University, St Louis] SHORT DESCRIPTION A soft, bioresorbable microfluidic cooling device engineered for reversible conduction block of peripheral nerves with integrated electronic feedback for precise temperature control. BACKGROUND Current...
Published: 2/13/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Bioresorbable Ultrasound Tags for Monitoring Deep Tissue Homeostasis
NU 2024-098 INVENTORS John Rogers* Chet Hammill [Washington University, St Louis ] Yonggang Huang Jiaqi Liu Naijia Liu Matthew MacEwan [Washington University, St Louis ] Mingzheng Wu Yameng Xu Haohui Zhang SHORT DESCRIPTION This technology features bioresorbable, shape-adaptive ultrasound tags that integrate flexible hydrogel matrices...
Published: 2/13/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Transient Closed-Loop System for Autonomous Cardiac Electrotherapy
SHORT DESCRIPTION For cardiac care providers, this novel system integrates wireless, body-integrated devices to provide autonomous, temporary electrotherapy. It improves patient mobility while reducing healthcare risks and costs. INVENTORS Igor Efimov* Professor of Biomedical Engineering and Medicine (Division of Cardiology),...
Published: 1/30/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Therapeutics
Modeling Personalized Disease Dynamics Using Liquid Biopsies for Tailored Treatment Strategies
NU 2025-187 INVENTORS Madhav Mani (PI - Northwestern University) Sidhartha Goyal* (PI - University of Toronto) Spencer Farrell (University of Toronto) SHORT DESCRIPTION This technology models disease progression using liquid biopsy data. It predicts individual tumor dynamics to support tailored treatment strategies. BACKGROUND Current approaches...
Published: 12/9/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Closed-Loop Implantable System for Automated Opioid Overdose Detection and Reversal
NU 2019-073 INVENTORS John Rogers (Northwestern University)* Robert Gereau (Washington University, St Louis)* SHORT DESCRIPTION This wireless device, the size of a pacemaker, is implanted to monitor oxygen levels. Below a specific threshold, it sends an alert to warning notification on a mobile app, then automatically releases naloxone to prevent...
Published: 12/9/2025   |   Inventor(s):  
Keywords(s): Drug delivery, Electronics & Circuits, Medical device, Microfluidics
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Therapeutics
Soft Bio-Integrated Catheter System
NU 2020-150 INVENTORS John Rogers (Northwestern University, Department of Materials Science and Engineering)* Igor Efimov (Northwestern University, Department of Biomedical Engineering, Medicine)* Roozbeh Ghaffari (Northwestern University, Department of Biomedical Engineering)* Mengdi Han SHORT DESCRIPTION This novel catheter platform delivers...
Published: 1/30/2026   |   Inventor(s):  
Keywords(s): Gene therapy, Sensors
Category(s): Life Sciences > Healthcare Devices, Tools & IT
A Biological Marker for Concussion
NU 2016-016 INVENTORS Nina Kraus* Trent Nicol Travis White-Schwoch SHORT DESCRIPTION This technology provides a method for objectively identifying non-penetrating brain injuries by analyzing the brain’s frequency following response (FFR) to an acoustic stimulus. It offers a non-invasive alternative that improves diagnostic precision and...
Published: 12/9/2025   |   Inventor(s):  
Keywords(s): Biomarker, Brain injury, Devices, Diagnostics, Electrophysiology, Health IT, Medical device, Neurologic disease, Research tool
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
AI-Driven 3D Detection and Treatment of Atrial Fibrillation
2024-092, 2023-222, 2020-103 INVENTORS Markus Rottmann* SHORT DESCRIPTION This comprehensive technology platform introduces an innovative AI-driven system for precise detection and treatment of atrial fibrillation (AF) through advanced 3D mapping and bipolar ablation. BACKGROUND Atrial Fibrillation (AF) is an irregular rapid heart rhythm and...
Published: 11/7/2025   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Healthcare Devices, Tools & IT
Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169 INVENTORS Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN)) Brian Meckes Wuliang Zhang SHORT DESCRIPTION For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 12/9/2025   |   Inventor(s):  
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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