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A transient closed-loop system
PROPOSED TITLE (cut & paste into Alternate Title): Transient Closed-Loop System for Autonomous Cardiac Electrotherapy
NU NUMBER NU 2021-255
INVENTORS
Igor Efimov*
John Rogers*
Hyoyoung Jeong
Rose Yin
Yeonsik Choi
SHORT DESCRIPTION
For cardiac care providers, this novel system integrates wireless, body-integrated devices to provide autonomous,...
Published: 12/9/2025
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Inventor(s):
Keywords(s):
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Therapeutics
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Modeling Personalized Disease Dynamics Using Liquid Biopsies for Tailored Treatment Strategies
NU 2025-187
INVENTORS
Madhav Mani (PI - Northwestern University)
Sidhartha Goyal* (PI - University of Toronto)
Spencer Farrell (University of Toronto)
SHORT DESCRIPTION
This technology models disease progression using liquid biopsy data. It predicts individual tumor dynamics to support tailored treatment strategies.
BACKGROUND
Current approaches...
Published: 12/9/2025
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Inventor(s):
Keywords(s):
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Closed-Loop Implantable System for Automated Opioid Overdose Detection and Reversal
NU 2019-073
INVENTORS
John Rogers (Northwestern University)*
Robert Gereau (Washington University, St Louis)*
SHORT DESCRIPTION
This wireless device, the size of a pacemaker, is implanted to monitor oxygen levels. Below a specific threshold, it sends an alert to warning notification on a mobile app, then automatically releases naloxone to prevent...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Drug delivery, Electronics & Circuits, Medical device, Microfluidics
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Therapeutics
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Soft Bio-Integrated Catheter System
NU 2020-150
INVENTORS
John Rogers (Northwestern University, Department of Materials Science and Engineering)*
Igor Efimov (Northwestern University, Department of Biomedical Engineering, Medicine)*
Roozbeh Ghaffari (Northwestern University, Department of Biomedical Engineering)*
Mengdi Han
SHORT DESCRIPTION
This novel catheter platform delivers...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Gene therapy, Sensors
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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A Biological Marker for Concussion
NU 2016-016
INVENTORS
Nina Kraus*
Trent Nicol
Travis White-Schwoch
SHORT DESCRIPTION
This technology provides a method for objectively identifying non-penetrating brain injuries by analyzing the brain’s frequency following response (FFR) to an acoustic stimulus. It offers a non-invasive alternative that improves diagnostic precision and...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Biomarker, Brain injury, Devices, Diagnostics, Electrophysiology, Health IT, Medical device, Neurologic disease, Research tool
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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AI-Driven 3D Detection and Treatment of Atrial Fibrillation
2024-092, 2023-222, 2020-103
INVENTORS
Markus Rottmann*
SHORT DESCRIPTION
This comprehensive technology platform introduces an innovative AI-driven system for precise detection and treatment of atrial fibrillation (AF) through advanced 3D mapping and bipolar ablation.
BACKGROUND
Atrial Fibrillation (AF) is an irregular rapid heart rhythm and...
Published: 11/7/2025
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Inventor(s):
Keywords(s):
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Retinal Lesion Detection via Machine Teaching for Enhanced OCT Analysis
NU 2025-111
INVENTORS
Rukhsana Mirza* (No affiliation provided)
Donna Hooshmand
Emma Alexander
Hayden Sikora
Jay Bisen
Kristian Hammond
Laura Machlab
Michael Drakopoulos
Paul Bryar
SHORT DESCRIPTION
This machine teaching algorithm automatically identifies retinal ischemic perivascular lesions on OCT images. It reduces manual workload...
Published: 12/9/2025
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Inventor(s):
Keywords(s): CVA - Cerebrovascular Accident
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Identification of Atrial Fibrillation Progression via Integrated Electrogram and Imaging Analysis
NU 2023-222
INVENTORS
Markus Rottmann*
SHORT DESCRIPTION
This invention integrates advanced analysis of atrial fibrillation electrograms and T1/T2 imaging to identify the progression state of AF. It offers clinicians a predictive tool to tailor treatment strategies and improve patient management.
BACKGROUND
Atrial fibrillation shows distinct...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Cardiology and Cardiovascular disease
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Morphology Recurrence Analysis for the Characterization of Atrial Fibrillation Electrograms
INVENTORS
Jeffrey Goldberger*
David Gordon
Jason Ng
SHORT DESCRIPTION
This technique uses modified recurrence analysis on electrogram data to identify patient-specific arrhythmia drivers. It supports precise, tailored ablation mapping for atrial fibrillation.
BACKGROUND
Traditional atrial fibrillation mapping struggles with dynamic, variable...
Published: 12/9/2025
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Inventor(s):
Keywords(s): Analysis, Biomedical, Cardiology and Cardiovascular disease, Computer software, Devices, Electrophysiology, Health IT, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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