|
A Rat Model of IgA Nephropathy
NU 2019-196
INVENTORS
Jing Jin*
Xinfang Xie
SHORT DESCRIPTION
A novel rat model of IgA nephropathy (IgAN, also known as Berger's disease), enabling reproducible kidney mesangial deposits characteristic of the human disease for therapeutic and diagnostic evaluation.
BACKGROUND
IgAN, the most common glomerulonephritis worldwide, results...
Published: 2/26/2026
|
Updated: 2/26/2026
|
Inventor(s):
Keywords(s): Animal Model, Antibody, Renal Disease
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Extracellular vesicles for diagnosis and treatment of breast cancer
SHORT DESCRIPTION
Novel methods for detecting cancer through exosome analysis and bioengineered exosomes specifically designed to target cancer stem cells (CSCs).
INVENTORS
Huiping Liu*, MD, PhD
Associate Professor, Pharmacology, Medicine (Hematology and Oncology), Northwestern University Feinberg School...
Published: 2/6/2026
|
Updated: 2/6/2026
|
Inventor(s):
Keywords(s): Biomarker, Breast cancer, Cancer/Oncology, Diagnostics, Imaging, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Focal Adhesion Proteins as Non-Invasive Diagnostics for Podocytopathies
SHORT DESCRIPTION
A diagnostic technology that detects focal adhesion complex proteins in bodily fluids for rapid and non-invasive identification of podocytopathies.
INVENTORS
Lorenzo Gallon*, MD
Robert Gerbasi
* Principal Investigator
NU Tech ID: 2019-056
IP STATUS
US Patent Pending
DEVELOPMENT STAGE
TRL-3...
Published: 2/5/2026
|
Updated: 1/30/2026
|
Inventor(s):
Keywords(s): Biomarker, Diagnostics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Projected Beam Pen Lithography for Benchtop High Resolution Maskless Photolithography of Large Areas
NU 2012-090
INVENTORS
Chad Mirkin (Northwestern University, Department of Chemistry)*
Keith Brown
Shu He
Guoliang Liu
Xing Liao
Wooyoung Shim
Abrin Schmucker
SHORT DESCRIPTION
This lithography system uses a projected beam pen method to directly pattern surfaces. It produces sub-100nm features quickly without the need for expensive masks.
BACKGROUND
Current...
Published: 12/9/2025
|
Updated: 11/11/2025
|
Inventor(s):
Keywords(s): Lithography, Nanomaterials, Nanotechnology, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
A Biological Marker for Concussion
NU 2016-016
INVENTORS
Nina Kraus*
Trent Nicol
Travis White-Schwoch
SHORT DESCRIPTION
This technology provides a method for objectively identifying non-penetrating brain injuries by analyzing the brain’s frequency following response (FFR) to an acoustic stimulus. It offers a non-invasive alternative that improves diagnostic precision and...
Published: 12/9/2025
|
Updated: 11/7/2025
|
Inventor(s):
Keywords(s): Biomarker, Brain injury, Devices, Diagnostics, Electrophysiology, Health IT, Medical device, Neurologic disease, Research tool
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
|
|
A platform for mapping reactive cysteines within the immunopeptidome
NU 2024-044
INVENTORS
Xiaoyu Zhang*
Chenlu Zhang
Chen Zhou
SHORT DESCRIPTION
This invention provides novel chemical probes for mapping reactive cysteine residues within the major histocompatibility complex class I (MHC-I) immunopeptidome.
BACKGROUND
The immune system's recognition of infected or malignant cells hinges on the presentation...
Published: 12/11/2025
|
Updated: 10/31/2025
|
Inventor(s):
Keywords(s): Biomarker, Immunology, Research reagent, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 12/9/2025
|
Updated: 10/30/2025
|
Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
|
|
TauSeeK: Disease Specific Tau Protein Fibrils & Seeding Proteins
NU 2024-154
INVENTORS
Songi Han*
Austin Dubose
Michael Vigers
Andrew Longhini
Vishnu Vijayan
Kenneth Kosik
Samuel Lobo
Peter C. Ryffel
Lokeswara Rao Potnuru
Karen Tsay
Chung-Ta Han
SHORT DESCRIPTION
Compositions, kits, and methods for generating synthetic miniature tau peptides and fibrils, and synthetic full-length pathogenic tau...
Published: 3/23/2026
|
Updated: 10/30/2025
|
Inventor(s):
Keywords(s): AD - Alzheimer’s Disease, Drug discovery, Drug screening, HD - Huntington's Disease, Neurodegenerative disease, Neurology, PD - Parkinson's Disease, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Synthetic Peptide Antigens to Detect Anti-Nephrin Autoantibodies
NU2025-147
Inventors
Jing Jin*
Pan Liu
Short Description
The invention provides a method for detecting anti-nephrin autoantibodies implicated in kidney diseases like minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS). This method employs synthetic peptide antigens for use as a clinical diagnostic.
Background
Kidney...
Published: 11/6/2025
|
Updated: 10/28/2025
|
Inventor(s):
Keywords(s):
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
|
|
Identification of Atrial Fibrillation Progression via Integrated Electrogram and Imaging Analysis
NU 2023-222
INVENTORS
Markus Rottmann*
SHORT DESCRIPTION
This invention integrates advanced analysis of atrial fibrillation electrograms and T1/T2 imaging to identify the progression state of AF. It offers clinicians a predictive tool to tailor treatment strategies and improve patient management.
BACKGROUND
Atrial fibrillation shows distinct...
Published: 12/9/2025
|
Updated: 10/28/2025
|
Inventor(s):
Keywords(s): Cardiology and Cardiovascular disease
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
|