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Projected Beam Pen Lithography for Benchtop High Resolution Maskless Photolithography of Large Areas
NU 2012-090
INVENTORS
Chad Mirkin (Northwestern University, Department of Chemistry)*
Keith Brown
Shu He
Guoliang Liu
Xing Liao
Wooyoung Shim
Abrin Schmucker
SHORT DESCRIPTION
This lithography system uses a projected beam pen method to directly pattern surfaces. It produces sub-100nm features quickly without the need for expensive masks.
BACKGROUND
Current...
Published: 11/11/2025
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Inventor(s):
Keywords(s): Lithography, Nanomaterials, Nanotechnology, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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A Biological Marker for Concussion
NU 2016-016
INVENTORS
Nina Kraus*
Trent Nicol
Travis White-Schwoch
SHORT DESCRIPTION
This technology provides a method for objectively identifying non-penetrating brain injuries by analyzing the brain’s frequency following response (FFR) to an acoustic stimulus. It offers a non-invasive alternative that improves diagnostic precision and...
Published: 11/7/2025
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Inventor(s):
Keywords(s): Biomarker, Brain injury, Devices, Diagnostics, Electrophysiology, Health IT, Medical device, Neurologic disease, Research tool
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 11/7/2025
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Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Synthetic Peptide Antigens to Detect Anti-Nephrin Autoantibodies
NU2025-147
Inventors
Jing Jin*
Pan Liu
Short Description
The invention provides a method for detecting anti-nephrin autoantibodies implicated in kidney diseases like minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS). This method employs synthetic peptide antigens for use as a clinical diagnostic.
Background
Kidney...
Published: 11/6/2025
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Inventor(s):
Keywords(s):
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Identification of Atrial Fibrillation Progression via Integrated Electrogram and Imaging Analysis
NU 2023-222
INVENTORS
Markus Rottmann*
SHORT DESCRIPTION
This invention integrates advanced analysis of atrial fibrillation electrograms and T1/T2 imaging to identify the progression state of AF. It offers clinicians a predictive tool to tailor treatment strategies and improve patient management.
BACKGROUND
Atrial fibrillation shows distinct...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cardiology and Cardiovascular disease
Category(s): Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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Nanocytological and Molecular Analysis of Fecal Colonocytes for Colon Cancer Screening
NU 2010-131
INVENTORS
Vadim Backman*
Dhwanil Damania
Dhananjay Kunte
Hariharan Subramanian
Hemant Roy
Mart De La Cruz
SHORT DESCRIPTION
This technology offers a novel fecal test that detects nanoarchitectural and molecular markers in colonocytes. It delivers a minimally invasive screening method for early detection of colon cancer.
BACKGROUND
Colorectal...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cancer/Oncology, Colon cancer, Diagnostics, Drug screening, Imaging, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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iPSCs derived from endometriosis and PCOS patients
NU 2025-155
INVENTORS
Ji-Yong Kim*
Teresa Woodruff
SHORT DESCRIPTION
Induced pluripotent stem cells (iPSCs) were generated from peripheral blood mononuclear cells (PBMCs) of women diagnosed with endometriosis or polycystic ovary syndrome (PCOS).
BACKGROUND
Endometriosis and PCOS are complex, multifactorial reproductive disorders that affect...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Cell Line, Drug screening, Obstetric/Gynecological, Stem cell
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Magnetic Resonance Contrast Agents for the Detection and Imaging of Senescence
NU 2024-024
INVENTORS
Thomas Meade*
Heike Daldrup-Link
SHORT DESCRIPTION
An MRI probe to detect senescent cells in vivo and in real-time.
BACKGROUND
Senescent cells promote osteoarthritis progression and are also found in cancer, virus infection, and other disease states. However, there is a lack of diagnostic tool to detect...
Published: 11/6/2025
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Inventor(s):
Keywords(s):
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Artificial Extracellular Matrix for Enhanced Maturation of Human iPSCs-derived Neurons
Artificial Extracellular Matrix for Enhanced Maturation of Human iPSCs-derived Neurons
NU 2018-157
Peptide amphiphile nanofibers enhance neuron maturation by promoting high mobility while reducing cell aggregation.
INVENTORS
Samuel I. Stupp
Zaida Alvarez Pinto
Juan Alberto Ortega Cano
Kohei Sato
Evangelos Kiskinis
SHORT DESCRIPTION
A...
Published: 11/6/2025
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Inventor(s):
Keywords(s): Neurology, Research tool
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Using human iPSC-derived bone marrow organoids to model human bone marrow diseases ex vivo
NU 2024-129
INVENTORS
Peng Ji*
Ermin Li
Kehan Ren
SHORT DESCRIPTION
Methods and factors for engrafting a bone marrow organoid with CD34+ hematopoietic stem and progenitor cells
BACKGROUND
Translational research for hematological diseases often relies on engrafting hematopoietic stem and progenitor cells (HSPCs) into immunodeficient mouse...
Published: 11/6/2025
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Inventor(s):
Keywords(s):
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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